Obesity Clinical Trial
Official title:
Glucose and Lipid Metabolism in Adolescents
A 12 wk aerobic exercise program will reduce visceral, hepatic and intramyocellular fat accumulation and improve insulin sensitivity and glucose metabolism in obese sedentary Hispanic adolescents.
Status | Recruiting |
Enrollment | 42 |
Est. completion date | December 2011 |
Est. primary completion date | December 2011 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 13 Years to 17 Years |
Eligibility |
Inclusion Criteria: - Healthy - No medication - Sedentary - No first degree relative with diabetes, - Hispanic - BMI >30 or <25 kg/m2. Exclusion Criteria: - Any medication including birth control pills - Performing more than >45 min of moderate to light physical activity/week - Chronic illness |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Baylor College of Medicine | Houston | Texas |
Lead Sponsor | Collaborator |
---|---|
National Institutes of Health (NIH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Fat distribution, insulin sensitivity, glucose production, gluconeogenesis, glycogenolysis | In response to a 12 wk exercise program. | No | |
Secondary | Lipolysis, blood lipids, adiponectin, leptin and CRP | In response to a 12 wk exercise program | No |
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