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Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin

Obesity Clinical Trial

Official title:
Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin

Clinical Trial Summary

The purpose of this study is to learn more about how insulin resistance (inability to process glucose correctly resulting in mildly elevated glucose levels) affects the hormone ghrelin.

Clinical Trial Description

Insulin resistance suppresses fasting ghrelin levels and impairs postprandial ghrelin suppression. Improved insulin sensitivity with a thiazolidinedione will raise ghrelin levels, enhance meal-related suppression, but not change the ratio of total to active ghrelin or result in an alteration of ghrelin structure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00843791
Study type Interventional
Source Oregon Health and Science University
Contact
Status Terminated
Phase N/A
Start date February 2009
Completion date May 2011
View Details
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