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Clinical Trial Summary

The overall purpose of this study is to examine the effect of calcium on fecal fat and energy excretion.


Clinical Trial Description

Several reports have found inverse associations between calcium intake and body weight. Few intervention studies have shown that a high calcium diet resulted in a greater body weight loss than a low calcium diet. The mechanism is not clear, but one possible explanation is reduced absorption of fat in the gut, due to formation of insoluble calcium fatty acid soaps or binding of bile acids which impairs the formation of micelles.

The aim of this study is to examined if a high calcium intake from dairy products, in diets high or normal in fat content, have an effect on fecal energy and fat excretion, concentrations of substrates involved in energy metabolism and blood pressure. ;


Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science


Related Conditions & MeSH terms


NCT number NCT00519909
Study type Interventional
Source University of Copenhagen
Contact Arne Astrup, Prof. MD
Phone +45 3533 2476
Email ast@life.ku.dk
Status Recruiting
Phase N/A
Start date August 2007
Completion date February 2008

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