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Non Invasive Ventilation : Efficacy of a New Ventilatory Mode in Patients With OHS

Obesity Hypoventilation Syndrome Clinical Trial

Official title:
Clinical Benefits and Tolerance to a New Ventilatory Mode in Patients With Obesity Hypoventilation Syndrome (OHS).

Clinical Trial Summary

In 2012, it has announced the availability of the new ventilator (BiPAP- A40), which could offer potential advantages over fixed level pressure support, in particular, in patients with obesity hypoventilation syndrome (OHS). One of the key benefits of the BiPAP A40 is an innovative ventilation mode called AVAPS-AE, which automatically maintains airway patency while delivering the correct level of ventilation each user requires, whatever their body position or sleep stage. AVAPS-AE mode is also aimed to help the clinicians during the initial titration of therapy, while providing long term comfort and assuring therapy compliance. However, studies on the physiologic and clinical effects have not yet been performed. The aim of our singled-blind randomised multicentre controlled trial is to prospectively investigate the effects of BiPAP with the spontaneous/timed (S/T) or the AVAPS-AE ventilation mode over 8 weeks on sleep quality, ventilation pattern, gas exchange, symptoms, body composition, level of physical activity and health-related quality of life in OHS patients.

Clinical Trial Description

Efficacy on sleep quality, symptoms, physical activity and quality of life ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01757444
Study type Interventional
Source Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Contact
Status Completed
Phase N/A
Start date June 2013
Completion date September 2018
View Details
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