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Nutritional Status clinical trials

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NCT ID: NCT01214785 Completed - Nutritional Status Clinical Trials

Cluster Randomised Trial of Improved Sanitation in Rural Orissa, India

Start date: September 2010
Phase: N/A
Study type: Interventional

The study is a cluster-randomized, controlled trial conducted among 100 villages (including approximately 3500 households and 20,000 people) in Puri district, State of Orissa, India. The study aims to assess the impact of the construction and use of latrines in rural settings on diarrhoeal disease, helminth infections and nutritional status. The study will also report on the cost and cost-effectiveness of the intervention and its impact on lost days at school and work as well as on expenditures on drugs and medical treatment. The study will document how the intervention actually impacts exposure to human excreta along principal transmission pathways by evaluating the impact on (i) faecal contamination of drinking water, (ii) the presence of mechanical vectors (flies) in food preparation areas, and (iii) the presence of faeces in and around participating households and villages. The study will also explore the extent to which different levels of acquisition and use of on-site sanitation among householders impact disease throughout the community.

NCT ID: NCT01209104 Completed - Nutritional Status Clinical Trials

Pharmacokinetics and Safety of GSK1325756 in Elderly Subjects and Adult Subjects of in the Fed and Fasted States and in the Presence of a Proton Pump Inhibitors

Start date: April 14, 2010
Phase: Phase 1
Study type: Interventional

GSK1325756 is a potent, competitive, selective and reversible CXCR2 receptor antagonist that is being developed as a once-daily oral anti-inflammatory medication for the treatment of chronic obstructive pulmonary disease (COPD). Selective antagonism of the interaction between CXCR2 and its various chemokine ligands is a potential strategy for reducing the underlying inflammation in COPD via the inhibition of neutrophil recruitment and activation. The current study explores the effects of age, gender and food (high fat meal) on the pharmacokinetics of GSK1325756. Because a significant proportion of COPD subjects are prescribed proton pump inhibitors (PPI's) such as omeprazole in order to alleviate symptoms of gastro-esophageal reflux disease (GERD), it is important to understand the absorption of the current formulation of GSK1325756 in an environment of raised intra-gastric pH as will be encountered in patients taking PPI's. Therefore, this study will also evaluate the impact of the proton pump inhibitor omeprazole on the pharmacokinetics of GSK1325756.

NCT ID: NCT01098123 Completed - Fatigue Clinical Trials

Metabolic Effects of Rowing Multi-races Events

Start date: April 2006
Phase: N/A
Study type: Observational

The aim of this study was to assess the relevance of NRI or athletes' NRI (ANRI) utilization to detect nutrition-related risks of failure in competition in the particular population of rowers. In the morning, 60 to 90 minutes before the first race of a national level multi-races competition (three races for each subjects), body weight were measured and blood samples were collected with subjects at rest and in post-absorptive condition (last meal at least 2.5 hours before blood collection). Body weight was also recorded in the same conditions six weeks before the competition to calculate weight state (actual weight /usual weight ´ 100) and subjects were asked to identify the date of diet beginning. Body weight was measured using a floor scale (Mettler-Toledo floor scale, France), body mass index (BMI) was calculated from the ratio of weight (in kg) by height squared (in meters) and training volume (total duration of training in a week) was determined after discussion with athletes and coaches.

NCT ID: NCT00938600 Completed - Pregnancy Clinical Trials

Antenatal Vitamin D3 Dose-finding and Safety Study

AViDD-1
Start date: July 2009
Phase: Phase 1
Study type: Interventional

This is a preliminary study of oral vitamin D3 supplementation in pregnant and non-pregnant women of reproductive age in Bangladesh. The primary objective of the study is to identify a dose of vitamin D3 that can safely be administered during pregnancy to improve the vitamin D status of the mother and infant.

NCT ID: NCT00876018 Completed - Physical Fitness Clinical Trials

Nutrition, Physical Performance & Fitness in Indian School Children

Start date: July 7, 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect of nutritional supplement on physical performance measures of apparently healthy school going children in India.

NCT ID: NCT00683527 Completed - Nutritional Status Clinical Trials

Timing of Iron Supplementation in Very Low Birth Weight Infants

Start date: May 2006
Phase: N/A
Study type: Interventional

To examine if early iron supplementation (starting oral iron at 14 days of life) would improve the nutritional iron status(measured by serum ferritin) of very low birth weight infants at postnatal age of 60 days, when compared to the standard regime of starting iron at 2 months of life.

NCT ID: NCT00564811 Completed - Hepatitis C Clinical Trials

Effect of Agaricus Blazei (Murrill) ss. Heinemann (Sun Mushroom)

Start date: March 2003
Phase: N/A
Study type: Interventional

The aim of the study was to verify the influence of Agaricus blazei (Murrill) ss. Heinemann (A. blazei) on the evolution of nutritional state and liver function in hepatitis C patients.

NCT ID: NCT00131625 Completed - Nutritional Status Clinical Trials

Impact of Exclusive Breast-Feeding in Guinea Bissau

Start date: March 2000
Phase: Phase 4
Study type: Interventional

Exclusive breastfeeding is promoted by the World Health Organization (WHO) with the aim of improving infant health. The specific objective of the study was to examine the effect of exclusive breast-feeding on morbidity and mortality in a randomised prospective study. Children born by mothers recorded as living in the study area during pregnancy was randomised at birth. WHO recommendations to postpone introduction of water and weaning food were told to the mother by 2-weekly home visits. All study children were followed from birth till 1 year of age according to morbidity, hospitalisation and mortality.

NCT ID: NCT00115271 Completed - Pregnancy Clinical Trials

Antenatal Micronutrient Supplementation and Birth Weight

Start date: January 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study was to determine the effects of providing supplements containing alternative combinations of micronutrients during pregnancy on birth weight and other infant and maternal health and nutritional outcomes in a rural area of Nepal.