Clinical Trials Logo

NSCLC clinical trials

View clinical trials related to NSCLC.

Filter by:

NCT ID: NCT03766958 Completed - NSCLC Clinical Trials

A Registry to Evaluate the Performance of the BDX-XL2 Test

ORACLE
Start date: October 16, 2018
Phase:
Study type: Observational

The purpose of the ORACLE Registry is to demonstrate clinical utility of the BDX-XL2 test; specifically, the potential to reduce unnecessary invasive procedures, such as biopsies and surgeries, on benign lung nodules while not significantly increasing the number of malignant lung nodules routed to CT surveillance. Clinical data will be collected from participating patients to evaluate the impact of the BDX-XL2 test when used in the clinical management of recently identified lung nodules assessed to have a low to moderate risk of cancer.

NCT ID: NCT03758781 Completed - Clinical trials for Non-Small Cell Lung Cancer

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

Start date: February 13, 2019
Phase: Phase 1
Study type: Interventional

This study is to determine the safety of IRX-2 Regimen combined with Nivolumab in patients with recurrent metastatic solid tumors. Researchers believe that this combination will have a tolerable safety profile and will increase the response rate in comparison to Nivolumab alone.

NCT ID: NCT03744715 Terminated - Breast Cancer Clinical Trials

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

Start date: October 5, 2018
Phase: Phase 2
Study type: Interventional

This is an open-label extension study (Extension Study) designed to allow patients to continue to receive poziotinib treatment who have had previous exposure to poziotinib and/or are still receiving clinical benefit from treatment, as judged by the Investigator or treating physician. Patients must begin treatment in this study within 28 days after their last dose of poziotinib. This extension protocol is intended to provide clinical benefit of poziotinib to patients who are responding to treatment. The additional treatment is optional and voluntary.

NCT ID: NCT03741231 Completed - Melanoma Clinical Trials

18FDG-PET in Patients With Melanoma or NSCLC Treated With Immunotherapy

IMMUNOPET
Start date: March 1, 2018
Phase:
Study type: Observational

Study the EFS and OS according to 18FDG PET in patients with melanoma or non small cell lung cancer treated by immunotherapy.

NCT ID: NCT03718117 Completed - NSCLC Clinical Trials

Descriptive Observational Study ALK-2016-CPHG

ALK2016CPHG
Start date: January 3, 2017
Phase:
Study type: Observational [Patient Registry]

Descriptive Observational Study. Characteristics Of ALK-positive and ROS1-positive Adults Patients Non-Small Cell Lung Cancer (NSCLC) Treated With Crizotinib Within General Hospitals

NCT ID: NCT03689855 Completed - Clinical trials for Non-small Cell Lung Cancer

Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLC

RamAtezo-1
Start date: June 5, 2019
Phase: Phase 2
Study type: Interventional

Data suggests that combining ramucirumab with immunotherapy in non-small cell lung cancer (NSCLC) patients who have previously received immune checkpoint blockers (ICBs) may be more effective than traditional therapy. The investigators propose a pilot study to test the combination of ramucirumab and atezolizumab in patients with advanced-stage NSCLC patients previously treated with ICB.

NCT ID: NCT03656393 Recruiting - NSCLC Clinical Trials

To Evaluate the Efficacy and Safety of Gefitinib in Adjuvant Chemotherapy for Lung Adenocarcinoma

RCTACSCNSCLC
Start date: August 31, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy and safety of targeted gefitinib versus oral vinorelbine and carboplatin in EGFR-mutant NSCLC patients.

NCT ID: NCT03652077 Completed - Ovarian Cancer Clinical Trials

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Start date: September 24, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02390 in participants with select advanced malignancies.

NCT ID: NCT03636685 Not yet recruiting - NSCLC Clinical Trials

Study of Anlotinib Plus Chemotherapy as the First-line Treatment in Patients With Advanced NSCLC

Start date: August 15, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Non-small cell lung cancer has the highest morbidity and mortality in China,and platinum-based chemotherapy is the standard first-line treatment for the wild-type NSCLC,however the overall survival still less than one year.Anlotinib is a kinase inhibitor of receptor tyrosine with multi-targets, especially for VEGFR2、VEGFR3、PDGFRβ and c-Kit, which has strong effect of anti-angiogenesis.This study is aim to evaluate the efficacy and safety of the combination regimen of anlotinib plus platinum-based chemotherapy as first-line treatment for NSCLC.

NCT ID: NCT03634826 Recruiting - Lung Cancer Clinical Trials

Monitoring of Circulating Tumor DNA and Its Aberrant Methylation in the Surveillance of Surgical Lung Cancer Patients (MEDAL, MEthylation Based Dynamic Analysis for Lung Cancer).

MEDAL
Start date: August 15, 2018
Phase:
Study type: Observational

Conduct a prospective study to confirm the value of circulating tumor DNA and its aberrant methylation in longitudinal monitoring of surgical lung cancer patients.