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Plasma EBV DNA Monitoring in Post-treatment NPC Patients

Nasopharyngeal Carcinoma Clinical Trial

Official title:
Long-term Results of Plasma Epstein-Barr Virus DNA Monitoring In Nasopharyngeal Carcinoma After Curative Treatment

Clinical Trial Summary

Continuous regular monitoring of plasma EBV DNA in nasopharyngeal carcinoma (NPC) after treatment have rarely been investigated. The investigators try to analyze the long-term observational results (role in early relapse detection and impact on survival) in NPC patients after curative treatment.

Clinical Trial Description

The investigators enrolled 441 NPC patients who had finished finished curative radiotherapy with/without chemotherapy and no recurrence/metastasis before entry this study from five hospitals in Taiwan. Blood samples were collected on the day of enrollment and monitored once every 2-3 months for plasma EBV DNA measurement. After long-term observation, we analyze the impact of continuous plasma EBV DNA monitoring on the early dection of tumor relapse and do risk grouping for survival analyses according to the blood test results. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03973723
Study type Observational
Source Taichung Veterans General Hospital
Contact
Status Completed
Phase
Start date August 1, 2011
Completion date April 30, 2019
View Details
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