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No-Reflow Phenomenon clinical trials

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NCT ID: NCT05427786 Recruiting - Clinical trials for Coronary Artery Disease

A Study to Evaluate the Impact of Pre-procedural Intracoronary Nicorandil Injection to PREVENT reductioN Of decREased TIMI FLOW in Patients Who Undergoing Percutaneous Coronary Intervention for the Coronary Artery Disease

Start date: December 14, 2022
Phase: Phase 4
Study type: Interventional

The aim of this study was to determine the effect of intra-coronary administration of nicorandil on the prevention of lowering of coronary blood flow for high-risk plaque lesions defined as the high value of lipid core burden index in patients with coronary artery disease who require stent treatment.

NCT ID: NCT02831153 Recruiting - Depression Clinical Trials

Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method

STRAIN-TIMI
Start date: July 2016
Phase: N/A
Study type: Interventional

This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck Depression Inventory, State-Trait Anxiety Inventory, Hospital Anxiety and Depression Scale. State Anxiety Inventory will be fulfilled both before the intervention and after 1 hour the patients learned the results of the coronary angiography. The other scales will be performed after 1 hour the patients learned their results. Coronary flow will be assessed by TIMI (Thrombolysis In Myocardial Infarction) frame count method.

NCT ID: NCT02818127 Recruiting - Clinical trials for Coronary Artery Disease

Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI)

TCCT-TIMI
Start date: July 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate and describe the total coronary circulation time (TCCT) by using TIMI frame count method in patients performed coronary angiography. TCCT is described as an angiographic index which is the sum of the frame count of coronary artery and venous system. This study also evaluates the relationship between the diseases in arterial system such as coronary artery ectasia, coronary slow flow, coronary artery disease and coronary venous pathologies.

NCT ID: NCT01430884 Recruiting - Clinical trials for Coronary Heart Disease

Analysis of Human Coronary Aspirate

AHCA
Start date: April 2004
Phase: N/A
Study type: Observational

During elective percutaneous coronary intervention (PCI), both proximal and distal protection devices are used. The distal occlusion protection device temporarily occludes the vessel distal to the lesion during the intervention, thereby capturing both particular debris and soluble substances released from the lesion such that they can be aspirated and prevented from reaching the coronary microcirculation. Rather than simply discarding the material which is retrieved from use of protection devices, the investigators have recently taken advantage of this situation, sampled the particulate and soluble material and subjected it to a variety of analyses with the ultimate goal to have a better insight into the respective plaque composition and to correlate it to the individual imaging and clinical data. On the basis of such information the investigators aim to better understand the pathophysiology of plaque vulnerability and to possibly predict the clinical development of the individual patient.