Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy

Neuropathic Pain Clinical Trial

Official title: Impact of Vitamin D Supplementation on Reported Rates of Taxane-Induced Neuropathy

Status Recruiting

Clinical Trial Summary

This is a two-arm randomized clinical trial in which 80 participants with Vitamin D deficiency and scheduled to begin taxane-based chemotherapy will be randomized to either: 1) prescribed vitamin D replacement or 2) standard of care.

Clinical Trial Description

This is a two-arm randomized clinical trial in which 80 participants with Vitamin D deficiency and scheduled to begin taxane-based chemotherapy will be randomized to either: 1) prescribed vitamin D replacement or 2) standard of care (advised to take over the counter (OTC) vitamin D).

All participants will have blood drawn for serum vitamin D analysis at Weeks 4, 8, 12, and 24 in order to document Vitamin D levels and titrate vitamin D dose (if needed in the treatment arm). Participants in both arms will complete self-report measures of neuropathic pain at baseline, Week 12, and Week 24. ;

Related Conditions & MeSH terms

• Neuralgia
• Neuropathic Pain

• NCT number: NCT05259527
• Study type: Interventional
• Source: Virginia Commonwealth University
• Contact: Autumn Lanoye, PhD
• Phone: 804-828-4929
• Email: lanoyeam@vcu.edu
• Status: Recruiting
• Phase: Phase 2
• Start date: December 19, 2022
• Completion date: March 31, 2027