Clinical Trials Logo

Neurological Disease clinical trials

View clinical trials related to Neurological Disease.

Filter by:

NCT ID: NCT06270420 Recruiting - Motor Disorders Clinical Trials

Technological Devices and Home Automation System in Neurological Rehabilitation

SMART
Start date: February 5, 2023
Phase: N/A
Study type: Interventional

The use of home automation system may be useful in rehabilitation to collect data about the environment and the amount of therapy. Then, the data may be stored in a cloud and integrated with data collected during training provided by technological devices. The main goal of this longitudinal pilot study is to define the productivity of the rehabilitation room (i.e., HoSmartAI room) in the IRCCS San Camillo Hospital (Venice, Italy) service, where the investigators will install home automation sensors and treat patients with neurological disease using technological devices (e.g., robotic and virtual reality). The secondary goals are to define the patients' satisfaction, usability of the system and the clinical effect of treatments delivered with technological devices in the HoSmartAI room. The patient will be assessed to personalized the treatment based on their needs. The treatment will consist of 15 sessions (1h/day, 5day/week, 3 weeks). At the end of the study, the patients will be assessed to define any clinical improvements. Finally, the investigators will define the characteristics of the patients who will benefit from the rehabilitation provided in the HoSmartAI room.

NCT ID: NCT06235580 Recruiting - Autoimmune Diseases Clinical Trials

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions

IFN
Start date: December 1, 2014
Phase:
Study type: Observational

Over the past twenty years, Prof. Yanick Crow and his team have developed internationally recognized expertise in genetic pathologies affecting the immune and neurological systems. The pathologies studied have a particularly severe impact on patients' quality of life, with a high mortality rate and a significant risk of occurrence in affected families. These pathologies are rare, and very often under-diagnosed. To date, there is virtually no effective curative treatment. Prof. Crow's team operates at the frontier between clinical and research work, and from experience, the team knows that patients and families affected by these serious pathologies are often highly motivated to help research into the pathology that affects them. Initially, Prof. Crow's research focused primarily on the study of the genetic disease Aicardi-Goutières Syndrome (AGS). However, there is an undeniable clinical and pathological overlap between AGS and other forms of disease such as autoimmune systemic lupus erythematosus and many other genetic pathologies - e.g. familial lupus engelure, spondyloenchondromatosis and COPA syndrome. This is why research is being extended to all genetic diseases with immune and neurological dysfunctions.

NCT ID: NCT05970939 Not yet recruiting - Clinical trials for Neurological Disease

Development, Reliability and Validity of the Telerehabilitation Usability Questionnaire- TrUQ

Start date: July 28, 2023
Phase:
Study type: Observational

Neurological diseases are central nervous system diseases that cause an increase in the level of disability and limitations in daily life. Multiple Sclerosis (MS), stroke, and Parkinson's Disease (PD) are among the most common apparent neurological diseases, and epidemiological studies show that their prevalence has increased over time worldwide. Although MS, stroke, and PD have different causes and neurological aspects, they generally cause motor, sensory, and/or cognitive impairments, leading to restriction of the individual's activities and participation. Today, physiotherapy and rehabilitation approaches together with optimal medical and surgical treatment are the cornerstones of treatment for these diseases. Recently, it has been stated that various telerehabilitation interventions in the field of physiotherapy and rehabilitation may be an additional option to the rehabilitation approaches applied in the clinic. On the other hand, It is important to evaluate the level of usability in expanding the usability of telerehabilitation services and determining the best telerehabilitation service. For this reason, there is a need for questionnaires investigating the satisfaction level of physiotherapy and rehabilitation applied through telerehabilitation.

NCT ID: NCT05969379 Recruiting - Clinical trials for Neurological Disease

Investigational Biomarkers for Neurological Immune-related Adverse Events

NFL-ICI
Start date: May 1, 2022
Phase:
Study type: Observational

Neurological immune-related adverse events (n-irAEs) are an emerging group of disorders of patients with cancer treated with immune checkpoint inhibitors, presenting with heterogeneous clinical manifestations and of uncertain outcome. Novel genetic, inflammatory, and neurogenerative biomarkers could be associated with distinct phenotypes and different outcomes. To test this hypothesis, the study will provide: a phenotypic characterization and outcome assessment of patients with n-irAEs; the analysis of biomarkers of genetic predisposition (HLA and other immunity-related genes), inflammation (serum and cerebrospinal fluid [CSF] cytokines and autoantibodies, peripheral blood and CSF lymphocytes and other immune cells, neuroimaging), neurodegeneration (serum and CSF neurofilaments, neuroimaging) and their correlation with clinical features and outcome.

NCT ID: NCT05653089 Recruiting - Clinical trials for Neurological Disease

Positioning in Wheelchair Bound Patients

AAPO'G
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The choice of the most suitable chair as well as the improvement of the patient's positioning on this wheelchair is important to limit the discomfort, to prevent the risks of bedsores, the pains related to prolonged sitting and finally to support the interaction of the patient with its environment. The goal of this prospective, longitudinale, monocentric study is to evaluate the impact of standardized positioning in wheelchair-bound patients at risk of slipping. The main questions on the positioning actions are: - their actions impact of positioning actions on shear forces - their impact on sliding in the chair - their impact on the feeling of discomfort in the chair - their impact on the caregivers' feelings about the patient's difficulties (eating, transfers, sliding) Participation in this study will involve an increase in the number of transfers required for shear sheet placement and removal, as well as the time required for ischial measurement and the time to complete the (Tool for Assessing Wheelchair disComfort) TAWC questionnaire.

NCT ID: NCT05575674 Completed - Stroke Clinical Trials

Retrospective Study on Myoelectric Elbow-Wrist-Hand Orthosis User Outcomes

Start date: October 5, 2022
Phase:
Study type: Observational

The objective of this study is to retrospectively evaluate the outcomes and clinical benefits provided by this brace to adult patients with upper limb impairment or paralysis due to brachial plexus, stroke (CVA), spinal cord injury, or other neurological disease or injury.

NCT ID: NCT05536921 Completed - Clinical trials for Traumatic Brain Injury

Eye Tracking Technology in the Diagnosis of Neurological Patients

Start date: May 1, 2022
Phase:
Study type: Observational

Demonstrating that diagnostics of the state of consciousness and cognitive functions of patients with consciousness disorders performed using C-Eye X (based on eye-tracking technology) allows a more objective assessment of state of patients who were wrongly diagnosed based on popular methods using in a clinical practice (like behavioural scales on paper forms).

NCT ID: NCT05520554 Completed - Clinical trials for Neurological Disease

Development, Reliability and Validity of the Telerehabilitation Satisfaction Questionnaire- TrSQ

Start date: August 15, 2022
Phase:
Study type: Observational

Parkinson's disease (PD), stroke, and Multiple Sclerosis (MS) are the most common neurological diseases. Today, physiotherapy and rehabilitation approaches together with optimal medical and surgical treatment form the basis of treatment for these diseases. Recently, it has been stated that various telerehabilitation interventions in the field of physiotherapy and rehabilitation may be an additional option to the rehabilitation approaches applied in the clinic. In addition, there are benefits such as continuity in patient education and rehabilitation, saving time and expenditure of individuals on the road. However, some problems arise in this form of treatment. Especially weak internet connection, sometimes requiring technical knowledge and expensive equipment can reduce the participation and satisfaction level of individuals. It is also important to evaluate the level of satisfaction in expanding the usability of telerehabilitation services and determining the best telerehabilitation service. For this reason, there is a need for questionnaires investigating the satisfaction level of physiotherapy and rehabilitation applied through telerehabilitation.

NCT ID: NCT05089682 Terminated - Parkinson Disease Clinical Trials

Manipulating and Optimizing Brain Rhythms for Enhancement of Sleep

Start date: June 22, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether researchers can improve sleep quality in patients with deep brain stimulators by delivering targeted stimulation patterns during specific stages of sleep.

NCT ID: NCT04900896 Active, not recruiting - Stroke Clinical Trials

Outcome Measures Study on an Adult Myoelectric Elbow-Wrist-Hand Orthosis

Start date: May 11, 2021
Phase:
Study type: Observational

The objective of this study is to evaluate the therapeutic and functional gains of a myoelectric elbow-wrist-hand orthosis for adult individuals with upper limb impairments using repeated measures studies that combines both gross motion and quantitative function outcome measures.