Neurogenic Bladder Clinical Trial
Official title:
The Effects of Stroke Related Neurogenic Bladder on The Quality of Life: A Study of Turkish Population
This study investigated effects of the neurogenic bladder on the quality of life in stroke survivors. Patients were divided into two groups: the First group consisted of patients with neurogenic bladder and the Second group consisted of patients without neurogenic bladder.
Status | Completed |
Enrollment | 71 |
Est. completion date | December 15, 2015 |
Est. primary completion date | December 15, 2015 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 30 Years to 88 Years |
Eligibility |
Inclusion Criteria: - Hemorrhagic or ischemic stroke - No previous stroke history - Disease duration > 6 months Exclusion Criteria: - Patients with different stroke etiologies other than cerebrovascular events (such as traumatic and tumoral pathologies) - Previous multiple stroke history - Pre-stroke urinary complaints - Previous urogenital surgery history - Spinal Cord Injury (SCI) - Prostate volume of > 35ml documented with urinary ultrasonography - Bladder outlet obstruction - Poorly controlled Diabetes Mellitus (DM) - Concomitant neurological diseases such as Multiple Sclerosis and Parkinson's Disease - Anticholinergic, alpha agonist-antagonist drug use - Sensory and global aphasia - Severe communication impairment |
Country | Name | City | State |
---|---|---|---|
Turkey | Istanbul Physical Medicine and Rehabilitation Training and Research Hospital | Istanbul |
Lead Sponsor | Collaborator |
---|---|
Istanbul Physical Medicine Rehabilitation Training and Research Hospital |
Turkey,
Best KL, Ethans K, Craven BC, Noreau L, Hitzig SL. Identifying and classifying quality of life tools for neurogenic bladder function after spinal cord injury: A systematic review. J Spinal Cord Med. 2017 Sep;40(5):505-529. doi: 10.1080/10790268.2016.1226700. Epub 2016 Oct 13. Review. — View Citation
Kim KJ, Heo M, Chun IA, Jun HJ; PhDc, Lee JS, Jegal H, Yang YS. The relationship between stroke and quality of life in Korean adults: based on the 2010 Korean community health survey. J Phys Ther Sci. 2015 Jan;27(1):309-12. doi: 10.1589/jpts.27.309. Epub 2015 Jan 9. Review. — View Citation
Milsom I, Kaplan SA, Coyne KS, Sexton CC, Kopp ZS. Effect of bothersome overactive bladder symptoms on health-related quality of life, anxiety, depression, and treatment seeking in the United States: results from EpiLUTS. Urology. 2012 Jul;80(1):90-6. doi: 10.1016/j.urology.2012.04.004. — View Citation
Panfili Z, Metcalf M, Griebling TL. Contemporary Evaluation and Treatment of Poststroke Lower Urinary Tract Dysfunction. Urol Clin North Am. 2017 Aug;44(3):403-414. doi: 10.1016/j.ucl.2017.04.007. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Short Form-36 (SF-36) | Short Form-36 (SF-36) was used to evaluate the quality of life of the patients. The form consists of 36 items, which measure 8 dimensions. These include (1) Physical function, (2) Social function, (3) Pain, (4) Energy/vitality, (5) Role limitation due to emotional problems , (6) Role limitation due to physical health problems, (7) Mental health and (8) General perception of health. Each subscale is evaluated between 0-100 points. A higher score indicates the better health. | 15 minutes | |
Secondary | Beck Depression Inventory | Beck Depression Inventory was used to assess depressive signs. The scale consists of 21 items and the items are ordered from mild to severe. Evaluation is performed in a range of 0-63 points. The lower score indicates the better psychological profile. | 15 minutes | |
Secondary | Mini Mental Test (MMT) | Mini Mental Test (MMT) was used to evaluate the extent of cognitive impairment. MMT is divided into 5 main categories: orientation (10 points), memory (3 points), attention and calculation (5 points), recalling (3 points) and language (9 points). Total points is 30. Total score between 0-9 points is considered as severe cognitive impairment. Total score between 10-19 points is considered as moderate cognitive impairment. Total score between 20-23 points is considered as mild cognitive impairment. Total score between 24-30 points is considered as normal. | 15 minutes | |
Secondary | Brunnstrom scale | Brunnstrom scale is used to evaluate separately upper extremity, lower extremity or hand functions. Six stages are defined. Stage 1: No active movement, Stage 2: Mild spasticity, weak flexor-extensor synergy patterns, Stage 3: Marked spasticity, synergy patterns are evident, Stage 4: Some isolated movements other than synergy patterns can be seen, Stage 5: Decreased spasticity, most muscle activities are isolated, Stage 6: Phasic and well-coordinated isolated movements are performed. A higher point indicates the better status. | 15 minute | |
Secondary | Functional Ambulation Category | Functional Ambulation Category (FAC) was used to evaluate the functional status. FAC assesses human support for ambulation rather than assistive devices. FAC 0: nonfunctional ambulation, FAC 1: Ambulator- dependent for physical assistance level II FAC 2: Ambulator- dependent for physical assistance level I, FAC 3: Ambulator-dependent for supervision FAC 4: Ambulator-independent level surfaces only FAC 5: Ambulator-independent. A higher score indicates the better status. | 15 minute | |
Secondary | Barthel Index (BI) | Barthel Index (BI) evaluates functional independence in term of daily living activity. Total score is 100 points. A higher point indicates better functional status. | 15 minute |
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