Mycophenolate Mofetil in Pediatric Steroid Dependent Nephrotic Syndrome

Status Completed

Clinical Trial Summary

Idiopathic nephrotic syndrome is generally responsive to steroid therapy, but some patients need other immunosuppressants to reduce steroid dependency. The long-term use should be restricted due to adverse effects of cyclosporine, such as hypertension and nephrotoxicity.

Mycophenolate mofetil for steroid-dependent nephrotic syndrome has been reported to have similar efficacy and fewer undesirable effects to other drugs in mainly observational studies. To determine the efficacy of mycophenolate mofetil in the management of steroid-dependent nephrotic syndrome, the investigators designed this prospective randomized controlled study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01895894
Study type	Interventional
Source	Seoul National University Hospital
Contact
Status	Completed
Phase	Phase 4
Start date	September 2013
Completion date	December 2016

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02238418` - Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria.	Phase 4
Completed	`NCT01411982` - Role of PACAP in Nehprotic Syndrome	N/A
Recruiting	`NCT00308321` - Long Term Tapering or Standard Steroids for Nephrotic Syndrome	Phase 4
Active, not recruiting	`NCT03326037` - Study of The Association of Mutations in The NPHS2 Gene and Nephrotic Syndrome in Children and Adults in Middle East
Recruiting	`NCT01240564` - The Nephrotic Syndrome Study Network (NEPTUNE)	N/A
Completed	`NCT01252901` - Registry for Patients With Wilms' Tumor Suppressor Gene 1 (WT1) Mutation Associated Diseases	N/A
Completed	`NCT01197040` - Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome	Phase 3
Terminated	`NCT00883636` - Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental Glomerulosclerosis	N/A
Completed	`NCT00035334` - Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis	Phase 2/Phase 3
Terminated	`NCT00004466` - Pilot Study of Atorvastatin in Children With Chronic Hyperlipidemia Secondary to Nephrotic Syndrome	Phase 2
Terminated	`NCT04558892` - Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome.	Phase 2/Phase 3
Completed	`NCT02257697` - A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Refractory Nephrotic Syndrome	Phase 3
Completed	`NCT00362531` - Tacrolimus Combined With Prednisone Treatment of Idiopathic Membranous Nephropathy and Nephrotic Syndrome	Phase 2/Phase 3
Completed	`NCT00289328` - Glucocorticoid-induced Osteopenia in Children	N/A
Recruiting	`NCT04759274` - Diuretic Tuner Clinical Decision Support	N/A
Completed	`NCT00001212` - Drug Therapy in Lupus Nephropathy	Phase 2
Recruiting	`NCT05623033` - The Predictive Value of Dynamic Changes of CD4+T Lymphocytes in Primary Nephrotic Syndrome With Infection
Completed	`NCT03332420` - The Efficacy of Huaiqihuang Granule in Children With Primary Nephrotic Syndrome
Not yet recruiting	`NCT05904197` - Effectiveness of Educational Gamified Cards About Nephrotic Syndrome	N/A
Completed	`NCT02438982` - Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Dependent Nephrotic Syndrome	Phase 3