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Nephrectomy clinical trials

View clinical trials related to Nephrectomy.

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NCT ID: NCT06256120 Not yet recruiting - Acute Kidney Injury Clinical Trials

Effect of Fluid Regimen on Acute Kidney Injury

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

Postoperative acute kidney injury (AKI) is an important surgical complication that increases hospital stay and mortality when it occurs after kidney surgery. Studies investigating the effects of restrictive or liberal fluid regimen on postoperative AKI during radical/partial nephrectomy have given controversial results. It is important to recognize AKI early so that supportive treatments can be started early. Serum creatinine level, which is frequently used in the detection of AKI, increases late and causes a delay in diagnosis. It has been reported that cystatin C level increases earlier than creatinine in the diagnosis of AKI, so it can be used for early diagnosis.

NCT ID: NCT06119568 Recruiting - Nephrectomy Clinical Trials

Safety and Performance Assessment of a First Four Arms on Demand Open Robotic Solution for Assisted PN, RN and RP

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical investigation is to evaluate the safety and performance of the Bitrack System and its corresponding ElectroSurgical Endoscopic (ESE) instruments and Non-ElectroSurgical Endoscopic (NESE) instruments and accessories in patients with the indication of a robot assisted laparoscopic Radical Nephrectomy (RN), Partial Nephrectomy (PN) or Radical Prostatectomy (RP), as applicable. HYROS-PRnP is a confirmatory study in which the hypothesis of the primary endpoint is that the ESE/NESE instruments perform as intended when controlled by Bitrack System which operates exclusively under surgeon's orders. The study shall refer to safety and performance of Bitrack System together with its accessories and corresponding ESE/NESE instruments. This study includes the data collected up to 30 days post-surgery and provides the evidence that the tested medical devices fulfill the GSPR.

NCT ID: NCT05864040 Recruiting - Nephrectomy Clinical Trials

HYbrid RObotic Surgery in Urology

HYROS
Start date: April 11, 2023
Phase: N/A
Study type: Interventional

The HYbrid RObotic Surgery in urology (HYROS) study is an early feasibility clinical investigation of a new medical device under the commercial name of Bitrack System. Bitrack System is a surgical robot indicated to be used during urological surgical procedures, general abdominal laparoscopic surgical procedures, and gynecological laparoscopic surgical procedures. The Bitrack System also requires the specific single use of endoscopic (both electrosurgical -ESE- and non-electrosurgical -NESE-) surgical instruments. The purpose of this clinical investigation is to evaluate the safety and feasibility of the Bitrack System and its corresponding ESE and NESE instruments and accessories in patients with the indication of a robot assisted laparoscopic radical/simple nephrectomy. Additionally, this investigation will collect initial clinical evidence for the process of obtaining CE Mark

NCT ID: NCT05596669 Completed - Nephrectomy Clinical Trials

Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

Start date: September 1, 2021
Phase: Phase 1
Study type: Interventional

Ketamine and magnesium-ketamine are two analgesics that are being studied for use as adjuvants. They were shown to have anaesthetic and analgesic properties, and as a consequence of this finding, it has been postulated that they may have a role in minimising the requirement for analgesic drugs during the postoperative period. The major objective of the research was to examine the pain-relieving effects of ketamine vs ketamine magnesium infusion, as well as their influence on postoperative morphine consumption following nephrectomy; the secondary goal is to assess hemodynamic effects and pain severity.

NCT ID: NCT05498246 Completed - Nephrectomy Clinical Trials

Bipolar Coagulation Versus Suture Renorrhaphy in Laparoscopic Partial Nephrectomy

Start date: December 5, 2020
Phase: N/A
Study type: Interventional

To compare between bipolar coagulation of tumor bed in laparoscopic partial nephrectomy versus suture renorrhaphy

NCT ID: NCT05149196 Not yet recruiting - Acute Kidney Injury Clinical Trials

Goal-directed Hemodynamic Management and Acute Kidney Injury After Radical Nephrectomy

Start date: December 2022
Phase: N/A
Study type: Interventional

Radical nephrectomy is a standard operation for the treatment of renal cell carcinoma. However, acute kidney injury frequently occur after surgery. And the occurrence of acute kidney injury is associated with an increased risk of chronic kidney disease. Intraoperative hypotension is identified as an important risk factor of postoperative acute kidney injury. Preliminary studies showed that goal-directed hemodynamic management may reduce organ injury after surgery but requires further demonstration. We hypothesized that goal-directed hemodynamic therapy achieved by combining liquid therapy and vasopressors can reduce the incidence of acute kidney injury after radical nephrectomy. The purpose of this study was to investigate the effect of goal-directed hemodynamic management on the incidence of acute kidney injury in patients following radical nephrectomy.

NCT ID: NCT05106218 Not yet recruiting - Laparoscopy Clinical Trials

Assessment of the SurroundScope in Urologic Surgical Procedures

Start date: March 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate standard urological surgeries using the 270Surgical system vs same procedures using the standard scope

NCT ID: NCT04947644 Recruiting - Clinical trials for Erector Spinae Plane Block

Ultrasound-guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Open Nephrectomy

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

There are different case studies about the use of erector spinae block (ESPB ) in nephrectomy, but there are no enough randomized controlled studies about it until now so it will be one of the earliest studies that investigate the effect of ESPB to relief acute postoperative pain in patients undergoing open nephrectomy. Although ESPB and thoracic epidural analgesia blocks successfully reduced postoperative opioid consumption in previous studies, no study has ever compared their efficacy in postoperative analgesia of adult patients undergoing open nephrectomy under general anesthesia thus in this randomized comparative study we are aiming to fill this gap in the literature. The aim of this study is to compare the analgesic effect of ultrasound-guided continuous erector spinae plane block versus thoracic epidural analgesia in open nephrectomy for renal cancer patients.

NCT ID: NCT04703634 Completed - Nephrectomy Clinical Trials

The Effect of Ultrasound-guided Erector Spinae Block on Postoperative in Patients Undergoing Nephrectomy.

Start date: January 14, 2021
Phase: N/A
Study type: Interventional

The main purpose of this study is to evaluate the postoperative effect of erector spinae block in patients undergoing nephrectomy that causes both visceral and somatic pain.

NCT ID: NCT04686890 Completed - Clinical trials for Regional Anesthesia Morbidity

Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy

Start date: December 30, 2020
Phase: N/A
Study type: Interventional

The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions