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Clinical Trial Summary

The purpose of the Phase 1 study is comprised of single ascending-dose component (Part 1) and multiple ascending-dose component (Part 2) to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASKG712 in patients with neovascular age-related macular degeneration (nAMD).


Clinical Trial Description

The Part 1 of study is a multicenter, open-label, sequentially, single ascending-dose study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASKG712 in subjects with nAMD. The Part 2 of study is a multicenter, open-label, sequentially, multiple ascending-dose (3 doses) study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASKG712 in subjects with nAMD. Subjects will be sequentially enrolled into different dose-level cohorts following the "3+3" design to determine the maximum tolerated dose (MTD) or the maximum administered dose has been reached. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05456828
Study type Interventional
Source AskGene Pharma, Inc.
Contact Jing Chen, MD
Phone 086-15895835292
Email chenjing@ask-pharm.com
Status Recruiting
Phase Phase 1
Start date February 20, 2023
Completion date April 30, 2024

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