Radiofrequency Ablation of Malignant Pulmonary Nodules

Neoplasms Clinical Trial

Official title: Efficacy and Safety of Radiofrequency Ablation of Malignant Pulmonary Nodules

Status Active, not recruiting

Clinical Trial Summary

The objective of this study is to evaluate the outcomes of radiofrequency ablation in the treatment of patients with malignant pulmonary nodules（not exceed 3cm ）who are not suitable candidates for or refuse surgical resection.

Clinical Trial Description

Percutaneous radiofrequency ablation (RFA) is a minimally invasive technique widely used to treat solid tumors. Patients with malignant pulmonary nodules will undergo a series of CT- guided percutaneous RFA procedures. During the procedures，percutaneous needles will be inserted into the target tissues under CT guidance，the needles deliver thermal energy and then destroy the tumors by causing coagulation necrosis via tissue heating. The purpose of this study is to assess the effectiveness and safety of RFA in pulmonary nodules （maximum tumor diameter ≦30 mm） was 10 mm apart from the big trachea, primary bronchi, esophagus, great vessels，heart and pleura. Preoperative and postoperative evaluations，including recent laboratory tests evaluated and imaging studies reviewed，will be performed both before and after the procedures. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Carcinoma
• Multiple Pulmonary Nodules
• Neoplasms

• NCT number: NCT02629978
• Study type: Interventional
• Source: Chinese PLA General Hospital
• Status: Active, not recruiting
• Phase: N/A
• Start date: October 2015
• Completion date: October 2020