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Neoplasms clinical trials

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NCT ID: NCT06001723 Completed - Depression Clinical Trials

A Feasibility Study to Determine Whether the Botanical Garden Become a Region of Forest Therapy for Cancer Survivors

Start date: August 4, 2022
Phase: N/A
Study type: Interventional

The forest healing system is an important topic of alternative therapy in recent years. To investigates forest therapy's effectiveness in alleviating negative emotions among post-cancer patients. It compares therapy outcomes at Taipei Botanical Garden and Fushan Botanical Garden. Utilizing a pretest-posttest experimental design, a two-hour guided forest healing activity serves as the intervention method. Data collection involves instrumental tests and saliva samples.

NCT ID: NCT05950399 Completed - Clinical trials for Malignant Solid Neoplasm

Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk

Start date: June 29, 2015
Phase: N/A
Study type: Interventional

This clinical trial evaluates changes in cardiac (heart) function during stress echocardiography to screen for chemically induced cardiotoxicity in cancer patients at a high risk for developing heart failure. Some chemotherapeutic agents to treat certain types of cancers can induce cardiac dysfunction and heart failure. Currently there is no validated means of predicting which patients will go on to develop cardiac toxicity and heart failure following treatment with chemotherapeutic agents. Stress echocardiography is a test that uses ultrasound imaging to show how well the heart muscle is working to pump blood to the body during low intensity exercise. Stress echocardiography prior to and during cancer treatment may help doctors find cancer therapeutic related cardiac dysfunction sooner when it may be easier to treat.

NCT ID: NCT05930457 Completed - Clinical trials for Malignant Solid Tumors

Study of 64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors

Start date: July 26, 2023
Phase: Phase 1
Study type: Interventional

This is the study of 64Cu-FAPI-XT117, which is an prospective, single-arm phase I clinical study.

NCT ID: NCT05914142 Completed - Solid Tumor Clinical Trials

Study on the Safety and Effectiveness of Varian ProBeam Proton Therapy Equipment in the Treatment of Solid Tumors

Start date: December 15, 2022
Phase: N/A
Study type: Interventional

This study is a clinical trial of prospective, single-arm objective performance criteria. This trial will be conducted in clinical trial sites with a total of 47 subjects enrolled. All of subjects will be treated with radiation therapy using the medical device Varian ProBeam Proton Therapy System (ProBeam), aim to compare the data with objective performance criteria (OPC) to evaluate the effectiveness and safety of ProBeam radiotherapy system for oncology patients, providing a clinical basis for the medical device registration.

NCT ID: NCT05910541 Completed - Advanced Cancer Clinical Trials

The Efficacy of Multisession Mindful Breathing in Symptom Reduction Among Patients With Advanced Cancers

Start date: January 2, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to determine the efficacy of multisession mindful breathing in reducing symptoms among patients with advanced cancer. Adult patients with advanced cancer will be assessed using Edmonton Symptom Assessment System (ESAS) scoring system. Patients who scored ≥4 in at least two or more components in ESAS will be recruited and randomly assigned to either 4 daily-session of 30-minute mindful breathing and standard care or standard care alone.

NCT ID: NCT05908838 Completed - Clinical trials for Gastric Cancer (Diagnosis)

Clinical Study of Modified Banxia Xiexin Decoction Treatment on Gastric Cancer

Start date: January 1, 2017
Phase: Early Phase 1
Study type: Interventional

Research purpose To elucidate the effect mechanism and clinical effective of Modified Banxia Xiexin Decoction in the prevention and treatment of gastric cancer. From genes related to cell differentiation, proliferation, apoptosis, tumor invasion and metastasis, genes related to immune inflammation and immune escape and other possible aspects to elucidate the effective and mechanism of Modified Banxia Xiexin Decoction's treatment on gastric cancer

NCT ID: NCT05908773 Completed - Clinical trials for Advanced Solid Tumor

A Microdose Study of TTX-MC138-NODAGA-Cu64 in Subjects With Advanced Solid Tumors

Start date: April 4, 2023
Phase: Early Phase 1
Study type: Interventional

This is an open-label, single-center, single-arm, phase 0, microdose study in subjects with advanced solid tumors and radiographically confirmed metastases. The study will evaluate delivery of TTX-MC138-NODAGA-Cu64 radiographically and establish the PK and biodistribution of TTX-MC138-NODAGA-Cu64 as determined by PET-MRI. The study consists of 3 parts: a screening period, dosing period, and follow-up period. The estimated total duration of the study is approximately 46 days. Approximately 12 subjects with advanced metastatic solid tumors will be enrolled at 1 single site.

NCT ID: NCT05905614 Completed - Clinical trials for Advanced Solid Tumors

Phase I Clinical Study of SPH4336 Tablets in the Treatment of Advanced Solid Tumors

Start date: November 3, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This clinical study evaluated the safety and efficacy of SPH4336 in the treatment of advanced solid tumors.

NCT ID: NCT05888753 Completed - Outcome Assessment Clinical Trials

Textbook Outcome in Adrenal Neoplasms

Start date: September 1, 2022
Phase:
Study type: Observational

BACKGROUND: Textbook outcome (TO) is a multidimensional quality management tool that uses a set of traditional surgical measures to reflect an "ideal" surgical result for a particular pathology. The aim of the present study is to record the rate of TO in patients undergoing elective surgery for adrenal neoplasms. MATERIAL AND METHODS: Retrospective study of all patients undergoing scheduled adrenal neoplasms surgery at a Spanish university hospital from September January 2010 to December 2022. Emergency surgeries were excluded. The variables included in the definition of TO were: R0 resection, no Clavien-Dindo ≥IIIa complications, no prolonged stay, no readmissions, and no mortality in the first 30 days. The main objective of this study is to analyse the achievement of TO in a series of patients undergoing scheduled adrenal neoplasms resection at the Doctor Balmis General University Hospital in Alicante, Spain. The investigators compare the group of patients who achieve a TO result with the group of patients who do not. A univariable and multivariable analysis will be carry out in order to indentified the variables associated with TO.

NCT ID: NCT05888675 Completed - Clinical trials for Gastric Cancer (Diagnosis)

Clinical Study of Weifuchun Treatment on Gastric Cancer

Start date: July 1, 2016
Phase: Early Phase 1
Study type: Interventional

Research purpose To elucidate the effect mechanism and clinical effective of weifuchun in the prevention and treatment of gastric cancer. From genes related to cell differentiation, proliferation, apoptosis, tumor invasion and metastasis, genes related to immune inflammation and immune escape and other possible aspects to elucidate the effective and mechanism of weifuchun's treatment on gastric cancer.