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Clinical Trial Summary

Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical preparation , versus 2.5% NaOCl,in asymptomatic necrotic mandibular premolar treated in single visit.


Clinical Trial Description

The patients will be randomly divided into 2 groups. Intervention group (50% Commiphora Myrrh solution root canal irrigant) and control group (2.5% sodium hypochlorite root canal irrigant) Post-operative pain will be measured at 6,12,24,48 hours post-operatively The pain will be recorded using numerical rating scale Post-operative swelling will be measured at 6,12,24,48 hours post-operatively The swelling will be receded using visual swelling rating scale Number of analgesic tablets taken by the patient post-operatively. Up to 48 hours Amount of bacteria load reduction The intracanal bacterial load reduction will be determined using agar culture technique by counting the colony forming units per milliliter (CFI /ml) before and after root canal preparation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06310044
Study type Interventional
Source Cairo University
Contact Rahaf A Manzalawi, BDS
Phone 01150019478
Email rahaf.manzlawi@dentistry.cu.edu.eg
Status Not yet recruiting
Phase N/A
Start date May 1, 2024
Completion date January 1, 2025

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