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Necrosis clinical trials

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NCT ID: NCT00872573 Terminated - Clinical trials for Rheumatoid Arthritis

A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement

Start date: July 1, 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to monitor the stability of the C-Stem™ AMT hip within the thigh bone when used in the treatment of patients with hip joint disease requiring a total hip replacement. Patients who enter the study will be evaluated at regular intervals following hip surgery using patient, clinical, standard x-ray assessments and special x-rays which allow the stability of the implant to be determined.

NCT ID: NCT00872547 Terminated - Clinical trials for Rheumatoid Arthritis

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Start date: September 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to monitor the performance of a large metal-on-metal bearing from the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery or a total hip replacement. Patients who enter the study will be evaluated at regular intervals following hip surgery using patient, clinical and x-ray assessments. The Study was terminated with effect from 30th November 2011 following the completion of 2 year follow up assessments for those patients remaining in the study. Please note that prior to this decision DePuy voluntarily recalled the ASR products on 24 August 2010. Additional information regarding this voluntary recall and the follow-up of patients affected by the recall can be found at the following links http://www.mhra.gov.uk/Publications/Safetywarnings/MedicalDeviceAlerts/CON155761 and http://www.depuy.com/countries_list.

NCT ID: NCT00872222 Terminated - Clinical trials for Rheumatoid Arthritis

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Start date: January 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to monitor the performance of the Pinnacle™ Cup with a ceramic-on-ceramic bearing combination in the treatment of patients with hip joint disease requiring a total hip replacement. Patients who enter the study will be evaluated at regular intervals following hip surgery using patient, clinical and x-ray assessments.

NCT ID: NCT00867256 Terminated - Clinical trials for Rheumatoid Arthritis

Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System (G030265)

Start date: March 31, 2004
Phase: N/A
Study type: Interventional

To demonstrate the safety and efficacy of the Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System using a composite clinical success (CCS) primary endpoint.

NCT ID: NCT00833430 Terminated - Avascular Necrosis Clinical Trials

Avascular Necrosis (AVN) Long-Term Follow-up

Start date: June 2006
Phase: N/A
Study type: Observational

Long-term follow-up of IDE patients for publication

NCT ID: NCT00698750 Terminated - Clinical trials for Rheumatoid Arthritis

A Clinical Investigation of the Copeland™ Humeral Resurfacing Head

Start date: April 2004
Phase: N/A
Study type: Observational

The purpose of this study is to perform a five-year, prospective evaluation of the Copeland™ Humeral Resurfacing Head Prosthesis for outcome and durability. Relief of pain and restoration of function will determine long-term clinical outcome while durability will be measured by the absence of revisions.

NCT ID: NCT00698633 Terminated - Osteoarthritis Clinical Trials

A Clinical Investigation of the M2a- Taper™ Hip System

Start date: December 2001
Phase: N/A
Study type: Observational

The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- Taper™ Hip System

NCT ID: NCT00698503 Terminated - Osteoarthritis Clinical Trials

A Clinical Investigation of the M2a- 38™ Hip System

Start date: January 2002
Phase: N/A
Study type: Observational

The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a- 38™ Hip System

NCT ID: NCT00546598 Terminated - Osteoarthritis Clinical Trials

Post-approval Study of the DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System

Start date: January 1, 2006
Phase: Phase 4
Study type: Interventional

This study is being conducted to gather medium and long-term information regarding the performance and safety of the commercially available DURALOC® Option Ceramic-on-Ceramic Hip Prosthesis System.

NCT ID: NCT00412841 Terminated - Avascular Necrosis Clinical Trials

Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus Erythematosus

Start date: November 2002
Phase: Phase 2
Study type: Interventional

This study uses the cholesterol lowering drug atorvastatin, also known as lipitor, to show reduction of avascular necrosis in steroid treated lupus patients. Avascular necrosis is a disease resulting from the loss of blood supply to the bones which can cause the bone to collapse. The collapse of bone may require a surgical replacement of the joint and can be disabling for life. Avascular necrosis is presently not preventable but research has shown that lipid lowering drugs such as lipitor can reduce or prevent avascular necrosis in animals. We therefore hypothesize that lipitor will reduce the incidence of avascular necrosis in lupus patients taking high dose steroids.