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Necrosis clinical trials

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NCT ID: NCT03112785 Active, not recruiting - Surgical Treatment Clinical Trials

Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage Operations

Start date: March 17, 2011
Phase: N/A
Study type: Interventional

Main question: Will use of a stem design that allows anatomical reconstruction of the hip joint improve the outcome in terms of hip function and patient satisfaction without causing any adverse effects? Background: Total hip arthroplasty with use of the most well documented implants is a safe and cost-effective procedure. In the Swedish Hip Arthroplasty register the CLS stem has a 16 years implant survival of 97, 5 %. It is a classic design which requires resection of most of the neck. The stem also intrudes into the greater trochanter which in patients with certain types of proximal hip anatomy makes proper introduction of the stem difficult. Finally it has a standard stem length which will jeopardise future stem removal should there occur any late infection or instability problems. Short uncemented stems have been introduced to enable a more anatomic reconstruction of the hip joint and to cause less invasion of the femoral canal to facilitate future revision should it be necessary. A more conservative resection of neck could also be of value to improve the clinical outcome by improved hip function and patient satisfaction. Purpose of the present study and design: In a prospective study the clinical outcome, stem fixation and bone remodelling around a short stem (Fitmore) will be studied. The main focus will be to evaluate patient reported outcomes especially concerning function, over all satisfaction, pain and activity. All patients will receive the same cup (Trilogy). This cup is chosen because it has a very thorough documentation in prospective RSA studies and in the Swedish hip arthroplasty register. All cups will be supplied with insert made of high molecular polyethylene (Longevity). Number of hips in the study: 44 consecutive cases

NCT ID: NCT03111407 Completed - Knee Osteoarthritis Clinical Trials

iAssist vs. Conventional Instrumentation in Total Knee Arthroplasty

Start date: April 2014
Phase: N/A
Study type: Interventional

The purpose of this prospective study is to evaluate Zimmer® iASSISTâ„¢ with respect to radiographic, clinical and economic outcomes and compared to conventional instrumentation in primary total knee arthroplasty (NexGen or Persona knee implants).

NCT ID: NCT03100578 Completed - Pancreas Necrosis Clinical Trials

EUS-guided Transmural Drainage of Walled-off Pancreatic Necrosis: Plastic vs Metallic Protesis.

PROMETHEUS
Start date: June 27, 2017
Phase: N/A
Study type: Interventional

Randomized multicenter study comparing plastic stents and self-expanding metallic stents in the eus-guided transmural drainage of walled-off pancreatic necrosis. Spanish centers partners of the spanish society of digestive endoscopy.

NCT ID: NCT03090139 Completed - Crohn Disease Clinical Trials

Sub-optimal Response to Anti-Tumor Necrosis Factor's in Inflammatory Bowel Disease in Emerging Markets

Start date: March 28, 2017
Phase:
Study type: Observational

The purpose of this study is to establish the incidence of sub-optimal response to anti-TNF therapy in UC and CD participants.

NCT ID: NCT03084601 Completed - Postoperative Pain Clinical Trials

Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy

3-mixtatin
Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of the current study is to compare a newly introduced material which is a combination of triple mix antibiotics paste and anti-hyperlipidemia drug simvastatin, the new material is named 3MIX-TATIN & will be compared to triple antibiotic paste for management of necrotic primary molars by using lesion sterilization and tissue repair LSTR technique.

NCT ID: NCT03083015 Completed - Necrotic Pulp Clinical Trials

Pulp Revascularization Versus MTA Apexification

RCT
Start date: December 6, 2012
Phase: N/A
Study type: Interventional

This study compared the efficiency of pulp revascularization and MTA apexification in the treatment of patients with necrotic immature anterior teeth.

NCT ID: NCT03067753 Recruiting - Clinical trials for Cerebral Radiation Necrosis

Monosialoganglioside Ganglioside in Cerebral Radiation Necrosis

Start date: December 2016
Phase: Phase 2
Study type: Interventional

Monosialoganglioside Ganglioside in Cerebral Radiation Necrosis

NCT ID: NCT03059290 Not yet recruiting - Necrotic Pulp Clinical Trials

Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File)

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

this prospective in vivo randomized clinical is to evaluate the post operative pain (incidence ,degree and duration) with multiple full rotation file (protaper next ®) and single full rotation file (Neolix®) in treating maxillary and mandibular anterior and premolar with chronic pulpitis .Together with our aim from this trial ; we are trying to provide an evidence for the dentists in order to provide the best quality service with the least expenses and thus gaining the patients' trust and saving time, money and effort.

NCT ID: NCT03048201 Recruiting - Clinical trials for Rheumatoid Arthritis

Physica System Total Knee Replacement Registry Study

Start date: March 24, 2017
Phase: N/A
Study type: Interventional

The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.

NCT ID: NCT03040778 Enrolling by invitation - Avascular Necrosis Clinical Trials

Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ)

Start date: April 1, 2018
Phase: Phase 3
Study type: Interventional

The overall purpose of this project is to answer the following clinical question: Among Medication-Related Osteonecrosis of the Jaw (MRONJ) patients, do those who are treated with the Pentoxifylline and Tocopherol (PENTO) regimen and standard of care, when compared to those treated with standard of care alone, have decreased areas of exposed bone after one year of treatment?