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Nausea clinical trials

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NCT ID: NCT06022705 Recruiting - Clinical trials for Nausea, Postoperative

Evaluation of the Effect of APFEL Risk Score and Fasting Periods on Postoperative Nausea and/or Vomiting

Start date: August 28, 2023
Phase:
Study type: Observational [Patient Registry]

This study, it is aimed to determine the effect of Apfel risk score and fasting times on postoperative nausea and vomiting (PONV).

NCT ID: NCT06017284 Recruiting - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancer

PTCA199-5
Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of thalidomide on improving the quality of life for metastatic pancreatic cancer patients receiving gemcitabine and nab-paclitaxel chemotherapy.

NCT ID: NCT06017167 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: September 15, 2022
Phase: Phase 2
Study type: Interventional

The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The secondary outcomes are: - The severity of post operative nausea and vomiting. - Use of rescue antiemetic drugs. - Postoperative pain and sedation.

NCT ID: NCT05996887 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

Impact of ERAS on Postoperative Nausea and Vomiting After Sleeve

Start date: July 30, 2023
Phase: N/A
Study type: Interventional

The use of bariatric surgery in the treatment of severe obesity has several benefits in terms of sustainable weight loss, improvements, or resolution of several metabolic comorbidities as well as improved life expectancy. Gastric surgery, history of acid reflux and reduction in gastric size, in particular after laparoscopic sleeve gastrectomy (LSG), surgery may further contribute to postoperative nausea and vomiting (PONV). The combination of antiemetic drugs that act at different receptors is more effective than using only one drug in preventing PONV in patients with increased risk for these events.

NCT ID: NCT05988671 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Intraperitoneal Dexamethasone, Dexmedetomidine, and Dexamethasone-Dexmedetomidine Combination on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: August 10, 2023
Phase: Phase 3
Study type: Interventional

Nausea and vomiting are some of the most common complaints of patients after any anesthesia, which is often associated with postop-erative pain. The double-blind clinical trial study aimed to compare the prophylactic effect of dexamethasone and dexmedetomidine and their combination in reducing postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.

NCT ID: NCT05975385 Recruiting - Pain, Postoperative Clinical Trials

Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Start date: October 9, 2023
Phase: N/A
Study type: Interventional

The purpose is to find out if intraoperative acupuncture performed by needling PC 6 and LI4 point bilaterally, and Yin Tang point will help reduce the incidence postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy when added to a prophylactic regimen consisting of ondansetron and dexamethasone. The hypothesis is that the addition of this acupuncture treatment to ondansetron and dexamethasone given for prophylaxis will help reduce the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy when compared to patients receiving ondansetron and dexamethasone without acupuncture.

NCT ID: NCT05956899 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

Palonosetron vs Ondansetron In PONV Prophylaxis Among Idiopathic Scoliosis Patients

PONV
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare the effectiveness of two antiemetic drugs, palonosetron and ondansetron, when given alongside dexamethasone as a preventive measure against early and delayed postoperative nausea and vomiting (PONV) in adult and adolescent patients with idiopathic scoliosis undergoing posterior spinal fusion surgery under total intravenous anesthesia (TIVA). The main questions the study aims to answer are: - How effective is palonosetron compared to ondansetron, both combined with dexamethasone, in preventing PONV after scoliosis surgery? - Are there any differences in the need for rescue antiemetics, occurrence of adverse effects related to the study drugs, and patient satisfaction between the two treatment groups? Participants in the study will be randomly assigned to receive either palonosetron or ondansetron in addition to dexamethasone as part of their anesthesia and antiemetic regimen. The incidence and/ or severity of nausea, vomiting and retching will be assessed at 1 hour, 4 hours, 12 hours, 24 hours and 48 hours after surgery.

NCT ID: NCT05888818 Recruiting - Clinical trials for Postoperative Nausea and Vomiting

The Effect of Cold Application on Nausea and Vomiting in the Early Postoperative Period

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

As a result of the literature review, it has been seen that it has not yet been clarified whether cold application methods are effective on postoperative nausea and vomiting, and academic studies on this subject are needed. The aim of the planned study was to conduct a randomized controlled experimental study to evaluate the effect of the cold application method on nausea and vomiting and the need for antiemetic drugs in the early postoperative period. The research hypotheses are as follows: H1:Cold application method reduces nausea and vomiting in the early postoperative period. H1:The cold application method reduces the need for antiemetic drugs in the early postoperative period. H1:Cold application method in the early postoperative period increases patient satisfaction. Condition or disease: Postoperative nausea and vomiting,Postoperative antiemetic use status,Patient satisfaction,Effects of cold application method Intervention/treatment: There is an intervention group in which the cold application method is applied.

NCT ID: NCT05875077 Recruiting - Clinical trials for Nausea and Vomiting, Postoperative

Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and Vomiting

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Post-operative nausea and vomiting are a leading cause of recovery room delays and low patient satisfaction. Complications such as suture line tension, wound hemorrhage and dehiscence, elevated intracranial pressure, pulmonary aspiration, dehydration, and electrolyte imbalance have been linked to nausea and vomiting. Many studies were done to explore the effects of propofol and dexmedetomidine on the incidence of post operative nausea and vomiting (PONV). In this study, we will compare propofol infusion to dexmedetomidine infusion on the incidence of PONV in patients undergoing ureteroscopic procedures under spinal anesthesia in the age group from 18 to 60 years with more than one risk factor for PONV (female, history of PONV, non-smoking).

NCT ID: NCT05851625 Recruiting - Chemotherapy Effect Clinical Trials

Efficacy of Ear Acupuncture in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients

Start date: October 16, 2023
Phase: N/A
Study type: Interventional

Chemotherapy is a cancer therapy performed on advanced cancer with quite good success, but this therapy has quite a lot of side effects. Chemotherapy induced nausea and vomiting or commonly known as CINV, is a condition of nausea and vomiting experienced by cancer patients undergoing chemotherapy, with a prevalence of around 80% of all patients undergoing chemotherapy, and 40% has the potential to become severe. This study aims to determine the efficacy of a new acupuncture modality, namely the press needle, in preventing CINV symptoms in pediatric patients with cancer undergoing chemotherapy. The study was conducted using a randomized controlled clinical trial (RCT) design in 64 pediatric cancer patients undergoing chemotherapy who were randomized into 2 groups, namely: (1) standard medical therapy as the control group; and (2) a combination of standard therapy with press needle acupuncture as the treatment group. The ear acupuncture points used are Shenmen and Stomach, and one body acupuncture point is PC6. Outcome measurements were carried out in the form of the RINVR questionnaire to assess the intensity of nausea and vomiting measured at 4 times: (1) 3 days before chemotherapy; (2) days of chemotherapy; (3) 12 hours after chemotherapy; (4) 3 days after chemotherapy.