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Clinical Trial Summary

This is a prospective, single-center clinical trial in eccentric nasopharyngeal carcinoma (NPC) patients. The aim of this study is to evaluate the efficacy and safety of NBI combined with MRI-guided optimized CTV compared with conventional CTV, and to compare the radiotherapy-related adverse events and quality of life between the two groups.


Clinical Trial Description

All patients with eccentric nasopharyngeal carcinoma were selected on the basis of MRI findings and NBI endoscopy was performed in these patients. The patients were enrolled if both NBI endoscopy and MRI showed eccentric NPC. Patients with contralateral tissue mucosal abnormalities detected by NBI and confirmed by biopsy were excluded. Then the patients were randomly divided into an experimental group (Optimized CTV) or a control group (Conventional CTV) to evaluate the efficacy and safety of the two groups, as well as radiotherapy-related adverse events. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06167109
Study type Interventional
Source Chongqing University Cancer Hospital
Contact Yuwei Wang, M.M.
Phone 13436161758
Email 38664816@qq.com
Status Recruiting
Phase N/A
Start date October 20, 2023
Completion date October 2026