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Myopia clinical trials

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NCT ID: NCT06450132 Not yet recruiting - Myopia Clinical Trials

Changes in Eye Shape With Myopia Management Interventions

Start date: July 1, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses. The main questions it aims to answer are: - do low-dose atropine and soft multifocal contact lenses affect the shape of the peripheral eye? - are changes in peripheral eye shape from these interventions influenced by changes in the focusing system of the eye? Participants will: - have multiple different types of photos taken - have their prescription for glasses/contacts checked - have their eye health checked, including the use of dilating eye drops - be randomly assigned to use eye drops every night or wear special contact lenses daily instead of their typical contacts - will complete five study visits over the course of 12 months Researchers will compare young adults using low-dose atropine to those wearing soft multifocal contact lenses and to those using no intervention to see if using these interventions affects retinal shape.

NCT ID: NCT06408649 Not yet recruiting - Myopia Clinical Trials

Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)

Start date: August 2024
Phase:
Study type: Observational

The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad variety of patients through routine clinical practices.

NCT ID: NCT06405711 Not yet recruiting - Myopia, Progressive Clinical Trials

To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia

Start date: May 2024
Phase: N/A
Study type: Interventional

To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.

NCT ID: NCT06393855 Not yet recruiting - Myopia Clinical Trials

Base Curves of Bandage Contact Lenses and Their Effects on Post Trans-PRK Vision and Pain

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

The objective of this study was to investigate the impact of employing bandage contact lenses with a base curve of 8.4 mm versus 8.8 mm on visual recovery following Trans-PRK in patients characterized by steep corneas and high myopia.

NCT ID: NCT06392607 Not yet recruiting - Myopia Clinical Trials

Euclid Phoenix Lens Design Trial 2

Start date: May 2024
Phase: N/A
Study type: Interventional

Lens wettability and subjective comfort of Euclid orthokeratology lenses with and without an enhanced coating will be compared in 50 children. Axial elongation will be monitored in pediatric patients who qualify and consent.

NCT ID: NCT06389110 Not yet recruiting - Myopia Clinical Trials

Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.

Start date: December 30, 2024
Phase: Phase 3
Study type: Interventional

Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in intraocular pressure, changes in the amplitude of accommodation, compared to placebo, as a treatment to delay the progression of myopia and axial ocular elongation in children.

NCT ID: NCT06358755 Not yet recruiting - Myopia Clinical Trials

Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control

Start date: July 1, 2024
Phase: Phase 2
Study type: Interventional

The purpose of the study is to investigate the combination effect of optical defocus and low dose atropine on myopia control in schoolchildren.

NCT ID: NCT06266910 Not yet recruiting - Myopia Clinical Trials

Effects of Autostereoscopic 3D Visual Training on Binocular Vision Function of Myopes

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

This study intends to conduct a relatively comprehensive binocular visual function examination and follow-up on two groups of myopic subjects, one receiving autostereoscopic 3D vision training and the other receiving 2D vision training as a control. The aim is to explore the impact of autostereoscopic 3D vision training on the accommodation and convergence functions of myopes. Additionally, synchronized EEG-fNIRS signals will be collected to investigate whether changes in binocular visual function are accompanied by corresponding alterations in brain function.

NCT ID: NCT06265454 Not yet recruiting - Myopia Progression Clinical Trials

Low Dose Atropine Eye Drops in Myopic Egyptian Children

LAMP
Start date: September 1, 2024
Phase: Phase 2
Study type: Interventional

Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression. purpose of the study is to compare changes in axial length, anterior chamber depth, choroidal thickness, central corneal thickness and anterior scleral thickness among myopic children receiving atropine 0.05% or 0.01% and placebo.

NCT ID: NCT06264830 Not yet recruiting - Cataract Clinical Trials

3D Visualization System in Highly Myopic Cataract Operation

3D-HiMCO
Start date: June 2024
Phase: N/A
Study type: Interventional

This study aims to investigate the impact of depth of field differences between the use of the 3D imaging system (NGENUITY® 3D Visualization System, Alcon, TX, USA) and conventional optical microscope in cataract surgery for highly myopic patients on intraoperative parameters and outcomes.