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Myopia clinical trials

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NCT ID: NCT02642991 Completed - Myopia Clinical Trials

Dispensing Study for a New Study Lens

Start date: November 2015
Phase: N/A
Study type: Interventional

This study investigated the performance criteria over one week of daily wear to determine if the comfilcon A asphere lens (test) performed equivalently to the comfilcon A sphere (control) in terms of measurement and subjective ratings of visual performance.

NCT ID: NCT02642354 Completed - Myopia Clinical Trials

One Week Assessment of a Lens With a Novel Optical Profile

Start date: November 2015
Phase: N/A
Study type: Interventional

This study will investigate performance criteria over one week of daily wear to determine if the comfilcon A asphere lens (test) performs equivalently to the comfilcon A sphere (control) in terms of measurement and subjective ratings of visual performance. Both comfilcon A asphere lens (test) and comfilcon A sphere (control) are Coopervision lenses.

NCT ID: NCT02642341 Completed - Myopia Clinical Trials

One Week Assessment of a New Study Test Lens

Start date: November 2015
Phase: N/A
Study type: Interventional

This study will investigate performance criteria over one week of daily wear to determine if the comfilcon A asphere lens (test) performs equivalently to the comfilcon A sphere (control) in terms of measurement and subjective ratings of visual performance. Both comfilcon A asphere lens (test) and comfilcon A sphere (control) are Coopervision lenses.

NCT ID: NCT02637804 Completed - Myopia Clinical Trials

Daily Disposable Silicone Hydrogel Contact Lens, Stenfilcon A, Clinical Study

Start date: January 2016
Phase: N/A
Study type: Interventional

Clinical evaluation of stenfilcon A compared with narafilcon A and delefilcon A This is a total 120 subject, randomized, open label, bilateral wear, two week crossover study (each lens for 1 week) evaluating the clinical performance of stenfilcon A spherical lenses compared to narafilcon A or delefilcon A spherical lenses.

NCT ID: NCT02627157 Completed - Myopia Clinical Trials

Measurements of Corneal Biomechanical Properties Using a Dynamic Scheimpflug Analyzer for Young Healthy Adults in South Korea

Start date: December 2, 2015
Phase:
Study type: Observational

The human cornea is affected by the magnitude and velocity of both internal and external forces because the cornea has both static and dynamic resistance components. Considering these natures of the human cornea, many investigators have tried to demonstrate corneal biomechanical properties to understand these characteristics of the cornea. Corneal biomechanical properties are known to influence the accuracy of measurements in intraocular pressure (IOP) and are recognized as important factor to explain the susceptibility of development of glaucomatous damage. Until recently, the only instrument which enabled the in vivo measurements of the ocular biomechanical properties was ocular response analyzer (ORA, Reichert Ophthalmic Instruments, Depew, NY, USA).8 The ORA has been used to assess the biomechanical properties of the cornea according to the dynamic bidirectional applanation process. A dynamic Scheimpflug analyzer (corneal visualization Scheimpflug technology [Corvis ST], OCULUS, Wetzlar, Germany) has been introduced recently and has become a useful instrument for evaluating corneal biomechanical properties. The dynamic Scheimpflug analyzer captures the dynamic process of corneal deformation caused by an air puff using an ultra-high-speed Scheimpflug camera at a rate of up to 4,330 images per second. Until now, well-organized analysis on the normative data of the corneal biomechanical profiles measured with the dynamic Scheimpflug analyzer for young healthy adults has not been reported yet. Hence, in the present study, we aim to conduct normative data analysis for the corneal biomechanical properties with the dynamic Scheimpflug analyzer in a cohort of young healthy adults in South Korea.

NCT ID: NCT02625753 Completed - Myopia Clinical Trials

Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain

Start date: November 2014
Phase: Phase 3
Study type: Interventional

Compare the use of codeine/paracetamol against placebo for pain control after cornea photorefractive keratectomy (PRK).

NCT ID: NCT02588573 Completed - Myopia Clinical Trials

Overall Performance of a 1-day Silicone Hydrogel Lens When Habitual Soft Lens Wearers Are Refit

Start date: October 2015
Phase: N/A
Study type: Interventional

The objective of the study is to compare the overall subjective comfort profile over 8 hours of lens wear in two groups of habitual soft contact lens wearers (daily disposable hydrogel lenses and frequent replacement lenses) when refitted in to somofilcon A lenses.

NCT ID: NCT02583620 Completed - Myopia Clinical Trials

Identification of Genomic Loci Determining Susceptibility to the Development of High Myopia

ASSOMYP
Start date: September 2009
Phase: N/A
Study type: Interventional

Compelling evidence of genetic components in high myopia has been put forward by several studies. Twin cohorts, familial linkage studies and population studies has described at least 10 loci containing genes involved in the disease development. The investigators previously demonstrated novel linkage on chromosome 7q36 and chromosome 7p15 in French families. A new approach consisting of a case-control based population association study is underway in order to recover a high number of myopic subjects avoiding the limitation of familial cases. 1.8 millions polymorphic markers will be compared with emmetropic controls in order to recover loci associated with the disease in the population.

NCT ID: NCT02575911 Completed - Myopia Clinical Trials

Accuracy of LASIK Flaps Created With the LenSx® Femtosecond Laser - A Pilot Study

Start date: October 28, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the thickness accuracy of Laser-assisted in situ keratomileusis (LASIK) flaps created with the LenSx® Laser.

NCT ID: NCT02555722 Completed - Myopia Clinical Trials

Evaluation of the CooperVision, Inc. Fanfilcon A and Enfilcon A Daily Wear Contact Lenses When Used for Frequent Replacement for up to One (1) Month of Daily Wear

Start date: September 21, 2015
Phase: N/A
Study type: Interventional

This study is a masked, multi-center, daily wear, monthly replacement, bilateral, randomized, lens blocked (subjects remain in the same lens brand throughout the study) concurrent control study enrolling up to 90 subjects with a study duration of approximately three months. Subjects will be randomized into the study contact lenses in a two to one (2:1) ratio of fanfilcon A lens (test) to enfilcon A lens (control).