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Myopia clinical trials

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NCT ID: NCT03913338 Completed - Myopia Clinical Trials

Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia

Start date: July 24, 2014
Phase: N/A
Study type: Interventional

The objectives of this study are to evaluate the safety and efficacy of a treatment regimen for high myopia and myopic astigmatism: LASIK followed by crosslinking performed with the KXL Crosslinking-System and VibeX Xtra (Riboflavin Ophthalmic Solution, Avedro, USA), as compared to LASIK alone, with regards to regression of refractive outcome, as measured by manifest refraction spherical equivalent (MRSE) and keratometry.

NCT ID: NCT03888482 Completed - Myopia Clinical Trials

Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 2

Start date: April 26, 2019
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Clariti contact lenses.

NCT ID: NCT03888469 Completed - Myopia Clinical Trials

Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1

Start date: May 3, 2019
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.

NCT ID: NCT03881670 Completed - Myopia Clinical Trials

On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours

Start date: December 7, 2018
Phase: Phase 4
Study type: Interventional

The current study aims to systematically investigate the diurnal variation in the optical quality of soft contact lenses on eye throughout the day. Subject reported quality of vision will also be evaluated.

NCT ID: NCT03836898 Completed - Myopia Clinical Trials

Presbyopic Phakic Intraocular Lens for Myopia Correction

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

This is a prospective single-center study of implantations of the presbyopic version of phakic intraocular lens IPCL (EyeolUK, United Kingdom).

NCT ID: NCT03786861 Completed - Myopia Clinical Trials

Corneal WFG Versus AF Trans PRK in Myopic Patients With High Corneal HOA

Start date: January 12, 2017
Phase: N/A
Study type: Interventional

compare the efficacy, safety and predictability of corneal wavefront guided (WFG) and aberration free ablation in single-step transepithelial photorefractive keratectomy (TransPRK) in myopic patients with high pre-existing corneal higher order aberrations (HOAs).

NCT ID: NCT03774992 Completed - Myopia Clinical Trials

Clinical Study Of Nearsightedness, TReatment With Orthokeratology Lenses 2

CONTROL2
Start date: January 4, 2018
Phase: N/A
Study type: Interventional

Myopia is a common disease of the eye with increasing prevalence all over the world including Denmark where the prevalence has increased from 12,8% in 2004 among young adults (mean age 19,3 years) till 17,9% in 2017 among school children (mean age 15,4 years). High myopia is associated with an increasing risk of sight threatening complications such as retinal detachment, glaucoma, macular choroidal degeneration, and myopic choroidal neovascularization. In myopia the eye is elongated compared to an emmetropic eye. If the elongation of the eye can be controlled the progression of myopia can be controlled. Asian studies have shown reduction in axial length growth by 36-46% in children using orthokeratology contact lenses (OKL). OKL are custom fit, form stable lenses. During sleep the cornea is reshaped creating an emmetropic vision during the day, so no glasses or contact lenses are needed. In the CONTROL-study 60 Danish children aged six to 13 years were randomized 1:1 to either OKL (intervention group) or single vision spectacles (SVS) (control group) and followed for 18 months to compare changes in axial length (AL). In CONTROL2 the intervention group will be followed for another 18 month and the control group will be crossed over to OKL treatment. The aims of CONTROL2 is to: 1. Investigate changes in axial length after 3 years of OKL wear (DreamliteR, Procornea, Nederlands). 2. Investigate changes in progression rate 18 month before and after OKL wear. 3. Investigate correlations between changes in choroidal thickness and changes in AL. 4. Investigate the safety of OKL treatment (Efron score). 5. Investigate changes in quality of life before and after OKL treatment using Pediatric Refractive Error Profile 2 (PREP2). 6. Investigate correlations between AC/A-ratio, peripheral refraction and higher order aberrations on myopia progression.

NCT ID: NCT03762668 Completed - Myopia Clinical Trials

Performance Assessment of a Modified Daily Disposable Contact Lens

Start date: December 3, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to compare visual acuity between two daily disposable contact lenses.

NCT ID: NCT03761758 Completed - Myopia Clinical Trials

Tolerability of a Novel Spectacle Design With Reduced Peripheral Contrast

WALNUT
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Prospective, randomized, subject-masked 3-arm clinical study to assess the pediatric acceptability across three iterations of a novel spectacle lens design.

NCT ID: NCT03728218 Completed - Myopia Clinical Trials

Visual Outcomes for Toric Efficacy Study

VOTE
Start date: October 12, 2018
Phase: N/A
Study type: Interventional

This is a crossover study of two types of contact lenses (toric orthokeratology and soft multifocals). Primary aims are to quantify correction of astigmatism, subjective and objective visual performance, aberrometry, peripheral refraction and bacterial bioburden between toric orthokeratology and soft toric multifocal contact lenses.