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Myopia clinical trials

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NCT ID: NCT06452524 Completed - Myopia Clinical Trials

Prematurity and Ophthalmological Changes

Start date: September 1, 2021
Phase:
Study type: Observational [Patient Registry]

Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity

NCT ID: NCT06335212 Completed - Myopia Clinical Trials

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

Start date: June 1, 2019
Phase:
Study type: Observational

Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia progression and axial elongation. As such, multifocal soft contact lenses (MFCLs) have been utilized for myopia control in school-aged children, with variable efficacies. One potential explanation is that the actual peripheral myopic defocus an eye experiences during MFCL wear may not be identical to the Add power and not sufficient to reduce myopia progression. Our study investigated and compared the peripheral power profiles of myopic eyes when they were uncorrected and wore single vision contact lenses (SVCLs) and MFCLs of different Add powers. Methods: Subjects with -1.00 D to -10.00 D of myopia (SE, determined with manifest refraction) were custom fit with both single vision (SV) and MFCLs (+2.00 and +4.00 D Add; provided by Specialeyes) in both eyes. These Specialeyes MFCLs had an aspheric design with a standard total optical zone of 8.0mm. Cycloplegic central autorefraction was conducted with both Grand Seiko WAM-5500 open-field auto-refractor (Grand Seiko Co Ltd) and OPD OPD-Scan III Wavefront Aberrometer (Marco) on the subjects in the following conditions: (1) no CLs, (2) SVCLs, (3) MFCLs (+2.00D Add), and (4) MFCLs (+4.00D Add). Relative peripheral power profiles were measured using the OPD under the same 4 conditions after cycloplegia. Data in the right eye was used for analysis.

NCT ID: NCT06251154 Completed - Myopia Clinical Trials

Clinical Comparison of Two Soft Contact Lenses

Start date: December 11, 2023
Phase: N/A
Study type: Interventional

This study was designed to gather short-term clinical performance data for 2 soft contact lenses.

NCT ID: NCT06250920 Completed - Myopia Clinical Trials

Effect of Virtual Reality-Based Visual Training for Myopia Control in Children

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

To assess the efficacy and safety of virtual reality-based visual training (VRVT) in myopia control among children.

NCT ID: NCT06204211 Completed - High Myopia Clinical Trials

Genetic Research on High Myopic Individuals in Northern China

Start date: May 1, 2022
Phase:
Study type: Observational

HM, which can dramatically cripple the eyesight of those affected, is a rampant ophthalmic disorder around the globe. It is in recent years that substantial studies covering the relationship between distinct variations and HM susceptibility sprang expeditiously. However, these studies have not yielded sufficiently credible and universally significant conclusions. Consequently, the study is conducted by including HM subjects residing in Northern China to explicitly illustrate this issue.

NCT ID: NCT06185868 Completed - Human Myopia Model Clinical Trials

Clinical Research Plan for Human Myopia Models

Start date: May 1, 2022
Phase:
Study type: Observational

Collect optical biological parameters, refractive index data, and other related parameters of myopia and refractive errors in children and adolescents, and establish an optical model of myopia in children and adolescents.

NCT ID: NCT06172881 Completed - Myopia Clinical Trials

Novel Multifocal Soft Contact Lens Study

Start date: December 14, 2023
Phase: N/A
Study type: Interventional

A single site, open label protocol will be used to evaluate the safety and quality of vision of a novel soft contact lens. Habitual contact lens wearers will be asked to come to the study site for one visit. Ocular health assessments and visual acuity will be completed with both the study lens and without.

NCT ID: NCT06128486 Completed - Myopia Clinical Trials

Clinical Evaluation of the Safety and Efficacy of Yung Sheng 55 % Color Contact Lens

Start date: August 25, 2012
Phase: N/A
Study type: Interventional

This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 55% Color Contact Lens for vision correction.

NCT ID: NCT06128473 Completed - Myopia Clinical Trials

Clinical Evaluation of the Safety and Efficacy of Yung Sheng 38% Color Contact Lens

Start date: June 18, 2013
Phase: N/A
Study type: Interventional

This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 38% color contact lens for vision correction.

NCT ID: NCT06121531 Completed - Myopia Clinical Trials

A Prospective, Randomized, Double-blind, Parallel, Active-controlled Clinical Study of Silicone Hydrogel Monthly Soft Contact Lens for the Safety and Effectiveness in Visual Correction.

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

This was a prospective, randomized, double-blind, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Hydrogel Contact Lens for vision correction.