Clinical Trials Logo

Myopia, Progressive clinical trials

View clinical trials related to Myopia, Progressive.

Filter by:

NCT ID: NCT05894382 Recruiting - Myopia, Progressive Clinical Trials

Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control

Start date: June 3, 2023
Phase: N/A
Study type: Interventional

This study uses 1.585 double helix defocus lens PC lenses with a unique optical design that includes a globally coherent visible area and complementary left and right helices that can form clear images. In addition, the helical arrangement and reduced slit area can generate defocusing signals, inhibiting the development of myopia. Therefore, based on previous research, this study plans to evaluate the safety and effectiveness of 1.585 double helix defocus lens PC frame eyeglasses in controlling the progression of myopia in children and adolescents through a randomized controlled clinical trial.

NCT ID: NCT05881655 Recruiting - Myopia, Progressive Clinical Trials

Slow Myopia Progression With Different Irradiance Light

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

It is a prospective clinical control study on red light control myopia with specail design spectacles for 75 children in 3 groups. Study Groups with two different powers of 0.6 mW and 1.2 mW at wavelength of 650nm. The control group is to wear the same brand and design spectalces as those two study groups. In addition, the progression of myopia is usually accompanied by the changes in a variety of ocular parameters, such as refractive error, reduced submacular choroidal thickness, and prolonged length of the ocular axis length.The goal is to test which power (1.2mW and 0.6mW) is better in myopic children for 3 month's follow-up and also to test how to get better result with the increaing or decreasing lighting power for the total 6 month follow-up results .

NCT ID: NCT05773118 Withdrawn - Myopia, Progressive Clinical Trials

A Unified Index to Predict the Success Probability of Myopia Control

Start date: January 2025
Phase: N/A
Study type: Interventional

Orthokeratology lenses (OK-lens) and multifocal contact lenses (MFCL) are optical devices designed to slow down the progression of myopia. Both treatments a long-term commitment from doctors and patients. This study aims to develop a unified index to predict the success probability of myopia control at the early stage of treatment.

NCT ID: NCT05761795 Not yet recruiting - Myopia, Progressive Clinical Trials

Efficacy of IVMED-85 on Pediatric Myopia

Start date: February 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and preliminary efficacy of a 1-year course of IVMED-85 eye drops for the treatment of pediatric myopia by assessing its safety effects on visual acuity and its effect on the change and/or progression of myopia. The main question[s] it aims to answer are: - Does IVMED 85 improve visual acuity - Does IVMED 85 slow or otherwise change the progression of myopia Participants will use eyedrops twice a day for one year. Researchers will compare IVMED 85 to a placebo.

NCT ID: NCT05761379 Recruiting - Myopia, Progressive Clinical Trials

Clinical Study of Light Therapy to Control Myopia Progression in Children

Start date: March 28, 2023
Phase: N/A
Study type: Interventional

Low-lever red light therapy (LLLT) has been used to control myopia progression in China for a few years besides amblyopia therapy for a few decades. This study is to test the efficacy of PBM therapy to myopia children as well as to compare two types of PBM therapy to control myopia progression within one month.

NCT ID: NCT05760911 Not yet recruiting - Myopia, Progressive Clinical Trials

Myopia Prevention Through Monitoring and Motivating Outdoor Activities With Smartwatches

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The goal of this multi-center, randomized, parallel-controlled clinical trial is to evaluate the effectiveness of outdoor activities monitoring and motivating by smartwatches to prevent myopia progression in children. The main question it aims to answer are: 1. To evaluate the two-year change of spherical equivalent progression. 2. To evaluate the change in axial length, the incidence of myopia, the time of outdoor activity, the choroid thickness, and blood flow through the two-year intervention. Participants will wear smartwatches and receive Mini Program outdoor activity reminders and motivations. The required outdoor activity time is 2 hours from Monday to Friday and more than 2 hours on weekends. The control group will only wear smartwatches for monitoring. Researchers will compare the control group and the intervention group to see if outdoor activities can protect myopia or not.

NCT ID: NCT05756959 Recruiting - Myopia, Progressive Clinical Trials

Myopia Control Combined PBM With Myopic Defocus Lens in Children

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

To study the efficacy of myopi control with two methods: low lever red light and peripheral defocus spectacles with four groups and design with prospective, double-blind, randimized, and with control for 6 month.

NCT ID: NCT05683535 Completed - Myopia, Progressive Clinical Trials

Adverse Events Related to Low Dose Atropine

AELDA
Start date: June 19, 2018
Phase:
Study type: Observational

Progressive myopia can lead to severe vision loss and is associated with retinal detachment, glaucoma, and other comorbidities. Several studies have shown that off-label, low-dose atropine eye drops slow the progression of myopia. Many eye care providers are now prescribing off-label atropine eye drops for their myopic patients, with the prescribed concentrations varying amongst providers. The purpose of this study is to determine if low-dose atropine eyedrops used daily, cause adverse effects to the eyes. Patients currently using 0.01%, 0.03%, or 0.05% atropine eye drops obtained from compounding pharmacies will be assessed for associated adverse effects.

NCT ID: NCT05597163 Not yet recruiting - Myopia, Progressive Clinical Trials

Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and Adolescents

LAMC
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

To investigate the efficacy and safety of three low-concentration atropine sulfate eye drops (0.01%, 0.025% and 0.05%) in controlling the progression of myopia in Chinese children and adolescents through a two-year clinical trial.

NCT ID: NCT05373693 Active, not recruiting - Myopia, Progressive Clinical Trials

Myopia-control Efficacy by Peripheral Defocus Lens (PDL)

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

The proposed study below aims to assess the effect of customized Bestivue PDL lenses on retinal image quality and myopia control. A total of 160 subjected would be enrolled in and randomized to allcoate into four groups. Visual acuity and image blur at various gaze directions and eccentricities on children fitted with +2 to 4 D power and single vision lenses would be measured to assess the short term effect of PDL lens. Axial length and cycloplegic objective refractive error would be measured to assess the Myopia-control Efficacy.