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Myopia, Progressive clinical trials

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NCT ID: NCT06088225 Recruiting - Myopia, Progressive Clinical Trials

Myopia Preventing With Distance-image Screen

DIS
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

This study is for testing the efficacy and safety of distance-image screens for preventing myopia in children for 12 month. Each subjects would be asked to paired test the ocular parameters between before and after 12-month distance-image screens.

NCT ID: NCT05939882 Recruiting - Myopia, Progressive Clinical Trials

Low Concentration Atropine in the Prevention of Myopia in Children.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

This double-blind, randomized controlled clinical study is to evaluate the effectiveness and safety of low concentration atropine in preventing myopia in pre-myopia children, and to explore whether there is a dose effect relationship between different concentrations of atropine in preventing myopia.

NCT ID: NCT05894382 Recruiting - Myopia, Progressive Clinical Trials

Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control

Start date: June 3, 2023
Phase: N/A
Study type: Interventional

This study uses 1.585 double helix defocus lens PC lenses with a unique optical design that includes a globally coherent visible area and complementary left and right helices that can form clear images. In addition, the helical arrangement and reduced slit area can generate defocusing signals, inhibiting the development of myopia. Therefore, based on previous research, this study plans to evaluate the safety and effectiveness of 1.585 double helix defocus lens PC frame eyeglasses in controlling the progression of myopia in children and adolescents through a randomized controlled clinical trial.

NCT ID: NCT05881655 Recruiting - Myopia, Progressive Clinical Trials

Slow Myopia Progression With Different Irradiance Light

Start date: May 20, 2023
Phase: N/A
Study type: Interventional

It is a prospective clinical control study on red light control myopia with specail design spectacles for 75 children in 3 groups. Study Groups with two different powers of 0.6 mW and 1.2 mW at wavelength of 650nm. The control group is to wear the same brand and design spectalces as those two study groups. In addition, the progression of myopia is usually accompanied by the changes in a variety of ocular parameters, such as refractive error, reduced submacular choroidal thickness, and prolonged length of the ocular axis length.The goal is to test which power (1.2mW and 0.6mW) is better in myopic children for 3 month's follow-up and also to test how to get better result with the increaing or decreasing lighting power for the total 6 month follow-up results .

NCT ID: NCT05761379 Recruiting - Myopia, Progressive Clinical Trials

Clinical Study of Light Therapy to Control Myopia Progression in Children

Start date: March 28, 2023
Phase: N/A
Study type: Interventional

Low-lever red light therapy (LLLT) has been used to control myopia progression in China for a few years besides amblyopia therapy for a few decades. This study is to test the efficacy of PBM therapy to myopia children as well as to compare two types of PBM therapy to control myopia progression within one month.

NCT ID: NCT05756959 Recruiting - Myopia, Progressive Clinical Trials

Myopia Control Combined PBM With Myopic Defocus Lens in Children

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

To study the efficacy of myopi control with two methods: low lever red light and peripheral defocus spectacles with four groups and design with prospective, double-blind, randimized, and with control for 6 month.

NCT ID: NCT04722874 Recruiting - Eye Diseases Clinical Trials

Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control

Start date: March 14, 2021
Phase: N/A
Study type: Interventional

The purpose of this multicenter randomized clinical trial is to evaluate the adjunctive effect of repeated low-level red-light therapy (RLRL) and orthokeratology (ortho-k) on myopia control in ortho-k non-responders who have undergone ortho-k treatment but were still experiencing fast myopia progression.

NCT ID: NCT03865160 Recruiting - Myopia, Progressive Clinical Trials

Low-dose Atropine for Myopia Control in Children

AIM
Start date: October 19, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Myopia (nearsightedness) is the most common eye disorder. Only second to age, it is the main risk factor for major degenerative eye diseases such as glaucoma, macular degeneration or retinal detachment. Their risk increases with the degree of myopia. Hence, prevention of myopia and slowing its progression is of high relevance. Almost all clinical studies, including two large randomised clinical trials (RCT) were performed in Asia with Asian study participants. The results indicate that atropine eye drops can attenuate myopic progression in children, even in low concentrations thus minimizing unwanted side effects. However, the cumulative evidence is yet not strong enough to recommend their unrestricted use, especially in a Non-Asian population. We therefore intend to set up an adequately powered RCT comparing atropine 0.02% eye drops with placebo to validate previous findings and to test whether this therapeutic concept holds its promise in a European population.

NCT ID: NCT03402100 Recruiting - Myopia, Progressive Clinical Trials

Eye Drops Study for Myopia Control in Schoolchildren

Start date: October 20, 2014
Phase: N/A
Study type: Interventional

The myopia prevalence in schoolchildren is high in Taiwan. The myopia progression is fast in children and often associated high myopia in later life. This prospective and randomized study to investigate the effect of myopia control in myopic children with ultra low concentrations of atropine eye drops and/or low concentrations of anti-allergic and inflammatory eye drops.