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Myopia, Progressive clinical trials

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NCT ID: NCT06405711 Not yet recruiting - Myopia, Progressive Clinical Trials

To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia

Start date: May 2024
Phase: N/A
Study type: Interventional

To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.

NCT ID: NCT06389110 Not yet recruiting - Myopia Clinical Trials

Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.

Start date: December 30, 2024
Phase: Phase 3
Study type: Interventional

Phase III clinical study to evaluate the efficacy of Alleance® (atropine sulfate 0.01%) ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in intraocular pressure, changes in the amplitude of accommodation, compared to placebo, as a treatment to delay the progression of myopia and axial ocular elongation in children.

NCT ID: NCT06221592 Not yet recruiting - Myopia, Progressive Clinical Trials

Differences and Wearing Safety and Comfort of New Defocus Incorporated Multiple Segments Spectacle Lenses

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of effective defocus micro lens design, and apply personalized defocus frame lenses for myopia prevention and control.

NCT ID: NCT06085430 Not yet recruiting - Myopia Clinical Trials

Kubota Glass Parameter Refinement Study

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Length of the eye will be measured in subjects exposed to various stimulus characteristics using an electronic spectacle which presents illuminated targets to the eye. The results will be analyzed to determine which stimulus characteristics may be most beneficial for use in the device.

NCT ID: NCT06071260 Not yet recruiting - Myopia, Progressive Clinical Trials

Effect of Atropine on Pupil Size and Quality of Vision

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

This aims to investigated the short-term (12, 16, and 20 h) effects of 0.01% atropine (0.1 mg/ml) on pupil size and subjective quality of vision in participants with myopia. Particpants will receive 0.01% atropine one drop to both eyes before bedtime. Baseline parameters were measured before atropine application. Changes in pupil sizes, under photopic and mesopic conditions, high-order aberration, and tear meniscus height were observed over the next day (12, 16, and 20 h).

NCT ID: NCT05955638 Not yet recruiting - Myopia, Progressive Clinical Trials

Management of Myopia in University Students Using Dual Focus Soft Contact Lenses

MoMUS
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The purpose of the study is to quantify the effectiveness of Coopervision MiSight contact lenses in slowing the rate of myopia progression in university students.

NCT ID: NCT05761795 Not yet recruiting - Myopia, Progressive Clinical Trials

Efficacy of IVMED-85 on Pediatric Myopia

Start date: February 2024
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and preliminary efficacy of a 1-year course of IVMED-85 eye drops for the treatment of pediatric myopia by assessing its safety effects on visual acuity and its effect on the change and/or progression of myopia. The main question[s] it aims to answer are: - Does IVMED 85 improve visual acuity - Does IVMED 85 slow or otherwise change the progression of myopia Participants will use eyedrops twice a day for one year. Researchers will compare IVMED 85 to a placebo.

NCT ID: NCT05760911 Not yet recruiting - Myopia, Progressive Clinical Trials

Myopia Prevention Through Monitoring and Motivating Outdoor Activities With Smartwatches

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

The goal of this multi-center, randomized, parallel-controlled clinical trial is to evaluate the effectiveness of outdoor activities monitoring and motivating by smartwatches to prevent myopia progression in children. The main question it aims to answer are: 1. To evaluate the two-year change of spherical equivalent progression. 2. To evaluate the change in axial length, the incidence of myopia, the time of outdoor activity, the choroid thickness, and blood flow through the two-year intervention. Participants will wear smartwatches and receive Mini Program outdoor activity reminders and motivations. The required outdoor activity time is 2 hours from Monday to Friday and more than 2 hours on weekends. The control group will only wear smartwatches for monitoring. Researchers will compare the control group and the intervention group to see if outdoor activities can protect myopia or not.

NCT ID: NCT05597163 Not yet recruiting - Myopia, Progressive Clinical Trials

Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and Adolescents

LAMC
Start date: January 15, 2023
Phase: N/A
Study type: Interventional

To investigate the efficacy and safety of three low-concentration atropine sulfate eye drops (0.01%, 0.025% and 0.05%) in controlling the progression of myopia in Chinese children and adolescents through a two-year clinical trial.

NCT ID: NCT04255524 Not yet recruiting - Myopia, Progressive Clinical Trials

Choroidal Change on OCTA in Eyes With High Myopia

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

Myopia is a global healthy concern, especially the high myopia and pathological myopia among Asian populations. However, its mechanism still remains largely unclear. Recent findings suggested choroidal changes might be related to the development of myopia. This study is to useOCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature change in myopic eyes, and try to find the cause-and-effect relationship between choroidal change and the development of myopia.