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Myofascial Pain Syndromes clinical trials

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NCT ID: NCT00550641 Completed - Fibromyalgia Clinical Trials

Pool-based Exercise in Fibromyalgia Management

Start date: March 2006
Phase: Phase 4
Study type: Interventional

Pharmacologic treatment remains the primary therapeutic approach in fibromyalgia management, but different non-pharmacologic measures, especially physical therapies and psychologically-based interventions, have also shown to be effective in the treatment of this disease. The objective of the present randomized controlled trial is to compare the efficacy and tolerability of two different modalities of active low-impact exercise in warm water: stretching and Ai Chi. Each group of patients will receive 18 physiotherapy sessions lasting 60 minutes and will be evaluated at baseline, at treatment termination, and after 4 and 12 weeks of follow up. Main outcome measures are the Fibromyalgia Impact Questionnaire (FIQ) and the Pittsburgh Sleep Quality Index (PSQI). Secondary outcome measures include the Beck Depression Inventory (BDI), the State and Trait Anxiety Inventory (STAI), and the SF-12 Health Survey (SF-12. Data analysis will be done using repeated measures ANOVA, unpaired Student's t test, and effect sizes' estimation (ES).

NCT ID: NCT00545649 Completed - Fibromyalgia Clinical Trials

Development of Treatments Aiming at Improvement of Function in Patients With Chronic Widespread Pain

Start date: May 2004
Phase: N/A
Study type: Interventional

The study aims to evaluate the effects of adding supervised exercise in supplement to an educational self-management program, and to determine which subgroups would gain effects of the treatment.

NCT ID: NCT00535587 Completed - Fibromyalgia Clinical Trials

Testing Mestinon and Exercise in Fibromyalgia

Start date: September 2002
Phase: Phase 2
Study type: Interventional

The purpose of this trial was to test the combined and independent effects of 6 months of exercise and Mestinon in people with fibromyalgia. Specifically, we wanted to determine if Mestinon helped people with fibromyalgia have an easier time exercising and if their symptoms improved by the end of the trial.

NCT ID: NCT00528710 Completed - Clinical trials for Fibromyalgia Syndrome

Efficacy of S-Adenosylmethionine in Fibromyalgia

Start date: November 2006
Phase: Phase 2
Study type: Interventional

Fundamentally, the trial aims to conduct a gold-standard test of the clinical impact of SAM-e in the treatment of depressed mood and general symptoms of fibromyalgia (FMS). As such, salient clinical and pathological parameters will be assessed over an 8-week period in 60 patients who will be provided with either SAM-e or a placebo preparation . On the basis of previous literature, it is hypothesised that patients in the active treatment group will experience moderate but significant improvements across the clinical measures, and that these gains will be significantly greater than any reported in the placebo group. All patients will provide informed consent. All procedures will be conducted under medical supervision and the preparation itself is very safe when used in the manner proposed for the trial

NCT ID: NCT00524420 Completed - Depression Clinical Trials

Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain

Start date: February 2008
Phase: Phase 2
Study type: Interventional

While acute pain after surgery or trauma comes on suddenly and lasts for a limited amount of time, chronic pain persists and can continue for months and even years. Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic field to deliver a current to the brain and can affect brain activity. The purpose of this study is to determine the effectiveness of rTMS treatment in reducing chronic widespread pain in women.

NCT ID: NCT00523302 Completed - Fibromyalgia Clinical Trials

A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia

TMS
Start date: July 2007
Phase: N/A
Study type: Interventional

In this pilot study, the PI proposes to include 20 African American participants with Fibromyalgia to explore the effect of r TMS on pain and depressive symptoms.

NCT ID: NCT00515008 Completed - Fibromyalgia Clinical Trials

Tai Chi Mind-Body Therapy for Fibromyalgia

Start date: June 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to obtain preliminary data on the effects of Tai Chi on musculoskeletal pain, fatigue, sleep quality, psychological distress, physical performance,and health status in 60 patients with fibromyalgia.

NCT ID: NCT00512590 Completed - Pain Clinical Trials

Pilot Study: Relaxation and Guided Imagery in Hispanic Persons Diagnosed With Fibromyalgia

Start date: April 2005
Phase: N/A
Study type: Interventional

The purpose of this pilot study was to test the effects of a 10-week relaxation and guided imagery intervention on pain perception, functional status, self-efficacy and levels of distress in Hispanic adults diagnosed with fibromyalgia.

NCT ID: NCT00497562 Completed - Fibromyalgia Clinical Trials

Growth Hormone as Add-on Treatment in Severe Fibromyalgia With Low IGF-1 Serum Levels (56 Characters)

Start date: May 2004
Phase: Phase 2
Study type: Interventional

There are evidences of functional growth hormone (GH) deficiency, expressed by means of low serum levels of insulin-like growth factor 1 (IGF-1), in a subset of fibromyalgia patients. The efficacy of low GH doses versus placebo has been demonstrated in this population. We assessed the efficacy and safety of GH added to standard therapy compared to standard therapy alone in the treatment of severe, prolonged and well-treated fibromialgya patients with low IGF-1 levels.

NCT ID: NCT00496886 Completed - Clinical trials for Rheumatoid Arthritis

Determining How the Nervous System Processes Pain in Adults With Fibromyalgia

Start date: April 2006
Phase: N/A
Study type: Observational

Fibromyalgia (FM) is a disabling chronic disorder characterized by widespread muscle pain, fatigue, and multiple tender points, specific places on the body that become painful with only slight pressure. Pain associated with FM cannot be explained medically, often leading to a delayed diagnosis and delayed treatment. The purpose of this study is to evaluate how the nervous system, specifically the brain, processes pain in women with FM.