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Myofascial Pain Syndromes clinical trials

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NCT ID: NCT00766350 Completed - Fibromyalgia Clinical Trials

Comparative Efficacy and Tolerability of Quetiapine XR and Amitriptyline in the Treatment of Fibromyalgia

Start date: November 2008
Phase: Phase 4
Study type: Interventional

Quetiapine, a second generation antipsychotic, has shown beneficial activity on fibromyalgia symptomatology, administered as add-on treatment, in a sample of 35 patients. The purpose of the present study is to compare, in a controlled setting, the efficacy and the tolerability of quetiapine extended release with amitriptyline in the treatment of patients with fibromyalgia

NCT ID: NCT00762125 Completed - Fibromyalgia Clinical Trials

Subgroups of Fibromyalgia Syndrome (FMS): Symptoms, Beliefs, and Tailored Treatment

Start date: December 2005
Phase: Phase 2
Study type: Interventional

Fibromyalgia syndrome (FMS) refers to a set of symptoms that include exhaustion, muscle pain, and tender points, where slight pressure can cause pain. Doctors do not know what causes FMS or how to cure it, but some treatments have helped relieve its symptoms. Progressive exercise, in which exercise is started at low levels and then increased, is one of the most reliable treatments, but people with FMS often avoid exercise or stop after completing exercise programs. This research will focus on the idea that people with FMS do not exercise because they are afraid of injury or have had a negative experience exercising. Participants will undergo one or a combination of several different treatments that aim to reduce fear of exercising. The different treatments will then be evaluated on their effectiveness in reducing disability among people with FMS.

NCT ID: NCT00760474 Completed - Fibromyalgia Clinical Trials

An fMRI Study Of Brain Response In Patients With Fibromyalgia

Start date: January 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to explore how pregabalin works in patients with fibromyalgia by evaluating brain imaging signals. To find out whether fMRI (functional magnetic resonance imaging) is an efficient way to show whether new pain medications are effective in treating fibromyalgia.

NCT ID: NCT00757731 Completed - Clinical trials for Fibromyalgia Syndrome

FMS European Long-Term Study

Start date: September 2006
Phase: Phase 3
Study type: Interventional

Investigation of the long-term (12 months) efficacy and safety of milnacipran used in the treatment of fibromyalgia syndrome.

NCT ID: NCT00757679 Completed - Clinical trials for Fibromyalgia Syndrome

Evaluation of the Antinociceptive and Analgesic Effects of Milnacipran

Start date: September 2006
Phase: Phase 2
Study type: Interventional

Evaluation of the antinociceptive effect of 7 weeks of treatment with milnacipran, compared to placebo, in fibromyalgia out-patients

NCT ID: NCT00752505 Completed - Fibromyalgia Clinical Trials

A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The study is designed to assess if esreboxetine can improve the cognitive function of patients with fibromyalgia. Cognitive function is defined as the ability to concentrate, remember things and make decisions or problem solve. The study is also designed to assess if there is a difference in cognitive function between fibromyalgia patients and matched control subjects.

NCT ID: NCT00750854 Completed - Osteoarthritis Clinical Trials

Efficacy & Safety Study of Natural Eggshell Membrane (NEM) for the Treatment of Joint & Connective Tissue Disorders

Start date: November 2003
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the use of the dietary supplement Natural Eggshell Membrane (NEM) for the treatment of joint and connective tissue discomfort & pain.

NCT ID: NCT00750230 Completed - Osteoarthritis Clinical Trials

Pilot Study of the Efficacy & Safety of Natural Eggshell Membrane (NEM) for Joint & Connective Tissue Disorders

Start date: October 2003
Phase: N/A
Study type: Interventional

The purpose of this study was to evaluate the use of the dietary supplement Natural Eggshell Membrane (NEM) for the treatment of joint and connective tissue discomfort, pain, and flexibility.

NCT ID: NCT00749983 Completed - Knee Osteoarthritis Clinical Trials

Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia

Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.

NCT ID: NCT00725101 Completed - Fibromyalgia Clinical Trials

Fibromyalgia Health Outcome Study on Cost of Treatments

REFLECTIONS
Start date: June 2008
Phase: N/A
Study type: Observational

The Real World Examination of Fibromyalgia: Longitudinal Evaluation of Costs and Treatments (REFLECTIONS) Study is a 12-month, prospective observational study that will be utilized in approximately 58 care settings in the United States (US) and Puerto Rico. It is designed to examine treatment patterns and health outcomes of adult participants diagnosed by their physician with fibromyalgia (FM) and who are starting any "new pharmacologic agent" for FM. The primary benefit of this study is enhanced understanding of the disease state of FM and the role that pharmacologic treatment plays, which may help to optimize management of FM. This study will address current gaps in a rapidly growing body of literature on FM.