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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT04522583
Other study ID # 2020-cardiology-1
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date September 2020
Est. completion date March 2021

Study information

Verified date August 2020
Source Hillel Yaffe Medical Center
Contact Simcha R Meisel, MD, MSC
Phone 972-52-3260931
Email meisel.simcha@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The investigators hypothesized that the CRP/troponin ratio measured in patients presenting to the ED with elevated troponin levels could differentiate between patients with cardiac ischemia and those who present due to a systemic inflammatory or infectious disease. The aim of the study was to determine the necessary CRP/troponin ratio required to rule out cardiac ischemia in a large ED population and determine its impact on long-term prognosis.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 15000
Est. completion date March 2021
Est. primary completion date January 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- All patients admitted to the ED in the period 2016-2019 with cTn level higher than the 99th percentile of cTn concentration in the normal population (>0.014 nanogram/milliliter).

Exclusion Criteria:

- None

Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
Diagnosis of Myocardial Ischemia
Discharge diagnosis of myocardial ischemia

Locations

Country Name City State
Israel Hille Yaffe Medical Center Hadera

Sponsors (1)

Lead Sponsor Collaborator
Hillel Yaffe Medical Center

Country where clinical trial is conducted

Israel, 

Outcome

Type Measure Description Time frame Safety issue
Primary Accuracy of the CRP/Troponin ratio The accuracy of the CRP/Troponin ratio in ruling out of myocardial ischemia according to the diagnosis of ischemia/coronary intervention at discharge analyzed by standard statistical measures Within 6 months
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