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Clinical Investigation of the Cardioprotective Effect of Early Administration of SGLT2 in Patients Presented With AMI

Myocardial Infarction Clinical Trial

Official title:
Clinical Investigation of Cardioprotective Effect of Early Administration of Sodium-glucose Cotransport-2 Inhibitors in Patients With Acute Myocardial Infarction

Clinical Trial Summary

This study aims to investigate the effect of early administration of DAPA during ischemia and before pPCI on infarct size, reperfusion injury-related myocardial damage, cardioprotection from HF, and renoprotection from AKI in patients with AMI.

Clinical Trial Description

DAPA was approved for HF patients, but there is no sufficient data about its efficacy on patients with AMI and if it can protect from the development of HF after AMI. the investigators aim to investigate the effect of DAPA on patients who presented with AMI when administered as early as possible before pPCI and to be continued for three months after there. the effect of DAPA on infarct size, cardiac biomarkers will be assessed during the follow-up period ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06009874
Study type Interventional
Source Tanta University
Contact Mohammad Soliman
Phone +201003474565
Email dr.mhtantawy@gmail.com
Status Recruiting
Phase N/A
Start date October 2023
Completion date August 2026
View Details
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