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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT04127591
Other study ID # XH-19-010
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date October 20, 2019
Est. completion date December 30, 2021

Study information

Verified date October 2019
Source Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Contact Bin He
Phone 021-25077828
Email hebinicu@139.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of this study is to determine the miRNA expression profile in peripheral blood exosomes of patients with myocardial infarction and to investigate its relationship with myocardial infarction.


Description:

Collect exosomes in peripheral blood of patients with myocardial infarction, compare the expression of miRNA with healthy volunteers, find out the miRNAs with significant differences, and explore its relationship with the development of myocardial infarction.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 10
Est. completion date December 30, 2021
Est. primary completion date December 30, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria:

- Age > 18 years ST elevation by ECG diagnostic of STEMI Evidency of coronary occlusion in coronariography Signed informed consent

Exclusion Criteria:

- Patients who will undergo immediate PCI Pregnant and lactating women Patients with mental disorders Patients are using other experimental drugs; Refusal to provide informed.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
exosome
Collect exosomes in peripheral blood of patients and extract miRNAs from them.

Locations

Country Name City State
China Ethics Committee of Xinhua Hospital Shanghai Shanghai

Sponsors (1)

Lead Sponsor Collaborator
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary Determination of differential expression of miRNA by second-generation sequencing technology Day 7
Secondary Diagnostic value of the differential microRNAs evaluate by qPCR in patients of myocardial infarction Day 7
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