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Clinical Trial Summary

ONASSIST is a registry of coronary ill patients who have had a functional test measuring anti-platelet effect and/or a genetic profile of response to anti-platelet drugs.


Clinical Trial Description

The Onassist Project is an assistance for cardiologists that establishes an individual risk of stent thrombosis for each patient based on:

- a functional approach (evaluation of the antiplatelet effect of the antiplatelet regimen by multiple tests) and

- a pharmacogenomic approach (genetic profile of response to antiplatelet agents) It provides advices for specific therapeutics after identification of adverse drug interactions, treatment compliance issues and true genetic, functional or mixed resistance.

This individualized strategy allow to adjust the choice of the drugs and their optimal dosage considering the best benefit - risk ratio.

Follow up are regularly made to identify markers of MACE (major adverse cardiac event) or bleeding. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02762162
Study type Observational [Patient Registry]
Source Action, France
Contact Jean Philippe COLLET, MD, PhD
Phone +33142162962
Email jean-philippe.collet@aphp.fr
Status Recruiting
Phase
Start date January 2007
Completion date January 2037

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