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Drug Drug Interactions of Aspirin and P2Y12-inhibitors

Myocardial Infarction Clinical Trial

Official title:
Drug Drug Interactions of Antiplatelet Drugs and Morphine

Clinical Trial Summary

Study Objective: To investigate potential drug-drug interactions (pharmacokinetics and pharmacodynamics) of morphine and antiplatelet drugs (aspirin, clopidogrel, prasugrel, ticagrelor)

Clinical Trial Description

Rationale: Opiates reduce the intestinal resorption of orally administered drugs such as paracetamol. Because morphine is often injected to relieve pain in patients with myocardial infarction, it is of particular interest if morphine may decrease the rate of absorption of antiplatelet drugs. Results of this study will provide essential information for the use of morphine and antiplatelet drugs in clinical practice, in particular in myocardial infarction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01369186
Study type Interventional
Source Medical University of Vienna
Contact
Status Completed
Phase Phase 4
Start date May 2011
Completion date January 2015
View Details
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