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Clinical Trial Summary

To explore the efficacy of venetoclax combined with azacytidine in Myelodysplastic / myeloproliferative neoplasms(MDS/MPN), so as to improve the overall survival and treatment status of MDS/MPN patients.


Clinical Trial Description

At present, there is no standardized treatment strategy for MDS/MPN. The purpose of our study is to explore the efficacy of venetoclax combined with azacytidine in the treatment of MDS/MPN, so as to improve the overall survival and treatment status of patients with MDS/MPN. After the participants were treated with four cycles of venetoclax combined with azacytidine, the efficacy was evaluated according to the 2015 adult MDS/MPN response criteria to determine the disease status. Participants with disease progression and intolerance withdrew from the study during treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05282719
Study type Interventional
Source The First Affiliated Hospital of Soochow University
Contact
Status Enrolling by invitation
Phase Phase 2
Start date April 2022
Completion date February 2023

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