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Muscle Strength clinical trials

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NCT ID: NCT03291483 Completed - Muscle Strength Clinical Trials

The Effects of Whole Body Vibration With Plyometric Training on Physical Performance in Basketball Players

WBV
Start date: January 20, 2016
Phase: N/A
Study type: Interventional

Purpose: The purpose of this study was to determine whether whole body vibration with plyometric training has effect on physical performance parameters and balance also this study searched for if vibration support additional benefits to normal plyometric training. Methods: 24 elite basketball players divided into two group as 12 players with the mean age of 24 ± 6,96 years (Study Group) and 12 players with the mean age of 22,45 ± 5,22 years (Control Group). Plyometric training were applied to study group on whole body vibration platform for 6 weeks (2 days/week) with routine basketball training, in control group plyometric training were applied on whole body vibration platform with the similar period of time but platform had been closed. All the assessments (physical measurement, vertical and horizontal jump tests, one-repetition maximum (1-RM) half squat strength test, 20 m speed test, T agility test, sit and reach flexibility test, star excursion balance test) were applied before and after 6 weeks plyometric training for both groups.

NCT ID: NCT03190304 Completed - Heart Failure Clinical Trials

The Effect of Neprilysin (LCZ696) on Exercise Tolerance in Patients With Heart Failure

NEPRIExTol
Start date: June 14, 2017
Phase: Phase 4
Study type: Interventional

Studies with new drugs in the treatment of heart failure (HF), such as the combination of valsartan/sacubitril, also known as LCZ696, have demonstrated important clinical impact on the morbidity and mortality outcomes in HF population. However, the effect of LCZ696 on the pathophysiological mechanisms of HF such as exercise tolerance (peak VO2) and peripheral muscle blood flow is not known. Since LCZ696 is a new drug with promising effects on the treatment of HF, the objective of the present study will be to evaluate the effect of LCZ696 in patients with HF on: 1) peak VO2, 2) 6-minute walk test, 3) peripheral muscle blood flow, 4) muscle strength, and 5) body composition.

NCT ID: NCT03150823 Completed - Muscle Strength Clinical Trials

Effects of Ascending and Descending Direct Current on the Handgrip Strength

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

Electrical stimulation currently has a wide range of clinical applications, being used for activities such as strengthening, pain control, edema management, or inflammation control after injury or surgery. One of the classic forms of electrotherapy is the Direct current (galvanic current), which stands out for its unique effects (polar and interpolar effects) and that are not achieved with other modalities of electrotherapy. Within these effects those activators or suppressors of nervous system activity are described. One of the applications of direct current is to produce sedation or excitation on the nervous system through longitudinal applications (longitudinal galvanization). This application technique is known as the upstream or downstream effect of the direct current or "Leduc Effect", in which it is postulated that an ascending type longitudinal galvanization has excitation effects of the central and / or peripheral nervous system. The study will evaluate the influence of the upward and downward direct current effect when performing a manual dynamometer test while monitoring by miofeedback in college students.

NCT ID: NCT02994641 Completed - Muscle Weakness Clinical Trials

Critical Care Observation of Motor Activity (COMA) and SICU Outcomes

COMA
Start date: December 2012
Phase: N/A
Study type: Observational

In the surgical intensive care unit (SICU), goals of critical care are often discussed in long-term ventilated patients around the time of extubation. Muscle weakness predicts extubation failure but formal muscle strength assessment by the Medical Research Council scale is time-consuming and not part of the daily clinical exam. In this observational study, we hypothesize that COMA measurement, routinely used by the SICU nurses, is a reliable and valid predictor for patients' SICU outcomes. This prospective observational study is carried out within a consecutively enrolled cohort of adult patients who are extubated in two SICUs at Massachusetts General Hospital, Boston.

NCT ID: NCT02968030 Completed - Aged Clinical Trials

Strengthening in Functional Mobility of Active Elderly

Start date: January 2008
Phase: N/A
Study type: Interventional

Aging is characterized by functional losses among which, the related to mobility and balance may be highlighted. Regular physical activity, including muscle strengthening exercises, is beneficial to a healthy elderly. Thus, this study aimed to verify the influence of 8 weeks-program of lower limbs strengthening exercises in the balance and functional mobility of physically active elderly. The investigators evaluated 18 women, with ages between 61 and 80 years. Balance assessment was performed using the Functional Reach Test (FRT), Timed Up and Go (TUG) test and Romberg test in stable or unstable soil. For muscular strengthening of the lower limbs, the workload was determined by the strength reached in the eight-repetition maximum test (8RM), applying progressive load increments between training sessions conducted (50% , 60% , 70% of 8RM), with the muscle strength being reevaluated in the fourth week of training, with subsequent adjustment of the load for the subsequent training. The training took place in two weekly meetings, in 40-minute sessions, during eight weeks. Data were analyzed using the paired-t test and ANOVA with repeated measures. Among 18 evaluated elderly women, 7 completed the 8 week training proposed. Decrease in TUG time (p = 0,035) and statistically significant increase in muscle strength were observed in all muscle groups trained (quadriceps, hamstrings, adductors and abductors). FRT (p = 0.170) was not significantly different after training. Therefore, strength training proposed was efficient in improving muscle strength in the lower limbs of irregular physically active elderly, impacting positively on functional gain gait. However, the gain in muscle strength was not enough to generate significant results in static balance probably due to the type of exercise performed as well as due being limited to muscle groups of the lower limbs.

NCT ID: NCT02884193 Completed - Muscle Strength Clinical Trials

Cold and Isometric Strength

Start date: April 30, 2019
Phase: N/A
Study type: Interventional

Cryotherapy has a wide range of clinical applications in rehabilitation, used for activities such as controlling inflammation, pain control or management of edema after an injury or surgery. In the field of cryotherapy they studied cold neuromuscular responses, where it has shown a decrease in nerve conduction velocity, which leads to a decrease in muscle strength. However it has been described in some work applications brief cold ("Quick Icing") may be opposite to those described effects, increasing the strength, the time of intervention the most important and decisive in these possible improvements or decreases factor. This effect is observed in response to a few seconds of application of cold, and would be given by an increased activity of motor neurons. Assess the influence of rapid cooling application ("Technique Quick Icing") and prolonged cooling in handgrip strength when performing a manual dynamometer test in college students.

NCT ID: NCT02797197 Completed - Sarcopenia Clinical Trials

Feasibility of Systematic Handgrip Strength (HGS) Testing and Short-term Changes in Muscle Strength in Digestive Cancer Patients Treated by Chemotherapy

FIGHTDIGO
Start date: May 18, 2016
Phase: N/A
Study type: Interventional

Sarcopenia is defined as a loss in skeletal muscle mass and function (strength and/or performance). There is a high prevalence in elderly and in patients with cancer. Several mechanisms are known to explain sarcopenia (inflammation, neurodegenerative process, hormonal disorders, lack of exercise, malnutrition). The consequences were analysed in several studies where sarcopenia appeared to be an independent factor of mortality, and associated with cancer-related fatigue, nosocomial infections, cardio-vascular diseases, and chemotherapy toxicities. Diagnosis is based on the measure of the muscle mass performing an abdominal computed-tomography (CT) scan, and on the measure of the muscle strength using the handgrip test with a "Jamar®" hydraulic hand dynamometer. CT scan is more invasive and less easy to reach than handgrip test. This test is used to be performing in elderly but not in cancer patients having chemotherapy. Present prospective study explored the feasibility of systematic handgrip strength testing and short-term changes in muscle strength in digestive cancer patients treated by chemotherapy.

NCT ID: NCT02775084 Completed - Cognitive Function Clinical Trials

Fish Oil T Cell Function

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to examine the effect of dietary n-3 polyunsaturated fatty acid supplementation on subjects' pan CD4+ T cell function, cognition, and muscle function. Half of the participants will receive fish oil, while the other half will receive a placebo (olive oil).

NCT ID: NCT02413112 Completed - Aging Clinical Trials

Get in Shape in the Team Research: Porukalla Kuntoon Tutkimus

PoKu
Start date: January 2015
Phase: N/A
Study type: Interventional

It is well accepted that physical activity in the form of resistance training produces a wide variety of neuromuscular-skeletal and health benefits. It is recommended in Finland that older individuals (over 65yr) should perform resistance training twice per week. Unfortunately, only approx. 5% of older individuals fulfill this recommendation. As Finnish society grows ever older, research should focus on the specific needs of this group and how to improve participation in physical activity, which may ultimately lead to modification of physical activity recommendations - resistance training recommendations are currently the same for young and older adults and do not include specific recommendations on the type of resistance training. However, these recommendations appear to have been developed for "best possible" improvements in maximum strength and muscle size. Therefore, it is of great importance to identify the number of resistance training sessions per week required to induce improvements in physical fitness, metabolic and bone health status, and importantly the reasons for adherence to/drop-out of resistance training interventions (e.g. motivation to train) in a multi-discipline study. This knowledge would benefit policy makers to update current recommendations for resistance training and to devise strategies to advise realistic targets for resistance training in the older, particularly the less-educated, age group (e.g. TELI-strategy for 2020). The present study will include a 12-month resistance training intervention with a 12-month follow-up period. Interviews and questionnaires will assess psychological/sociological data and will be collected from both drop-out subjects and those that complete the intervention. Neuromuscular performance and functional capacity will be tested using conventional methods, along with body composition, bone density, and blood tests for metabolic markers of health. Diet and other physical activity will be controlled throughout the intervention period. Measurements are to be performed every 3 months. It is expected that 5 international peer-reviewed articles will be published in 2016-2017. The data will be presented at international and national conferences in 2015-2017. Finally, results of the entire research will be published in national peer-reviewed journals (e.g. The Age Institute's "Raportteja"). All subjects will be invited to attend an information meeting where group results will be presented and explained.

NCT ID: NCT02406339 Completed - Muscle Strength Clinical Trials

Effectiveness of NMES Associated to Vascular Occlusion in Functional Performance and Muscle Hypertrophy in Athlete's

Start date: July 2014
Phase: N/A
Study type: Interventional

This study evaluates the effect of training with neuromuscular electrical stimulation (NMES) associated with vascular occlusion of the lower limbs, for increased strength and hypertrophy of the quadriceps muscle of professional basketball athletes.