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Muscle Relaxation clinical trials

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NCT ID: NCT05911867 Recruiting - Breast Cancer Clinical Trials

Muscle Energy Technique and Mulligan's Mobilization in Breast Cancer Surgery Patients

MWMMET
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

A recent study aimed to examine the combined effect of Mulligan and muscle energy techniques on postural changes and shoulder kinematics among women who had undergone breast cancer surgery with axillary dissection.

NCT ID: NCT05757999 Recruiting - Muscle Relaxation Clinical Trials

Effect of MgSO4 Pretreatment on Muscle Relaxation

MgSO4/CisA
Start date: July 23, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

In this study, the effect of magnesium sulphate on the onset and duration of intense and moderate cis-atracurium induced neuromuscular blocking and on the period of no response to nerve stimulation will be evaluated in patients who will recieve magnesium sulphate (intervention group) and patients who will not recieve magnesium sulphate (comparator group).

NCT ID: NCT05529420 Recruiting - Muscle Relaxation Clinical Trials

Interindividual Variability in Duration of Action of Rocuronium in Pediatric Patients

DurAct
Start date: September 5, 2022
Phase:
Study type: Observational

Muscle relaxants represent an important part of general anesthesia in adult and pediatric patients. Their role is to facilitate intubation and enable some surgical interventions. At our workplace, monitoring of the depth of neuromuscular blockade is a standard procedure in accordance with the 2017 recommendation of ČSARIM entitled "Principles of Patient Safety in Anesthesiology" [1,2]. At present, we mainly use rocuronium. One of the advantages of this non-depolarizing steroidal muscle relaxant with a rapid onset and intermediate duration of action is the existence of the specific antagonist sugammadex.

NCT ID: NCT03801785 Recruiting - Sleep Clinical Trials

Efficacy of Non-Nutritive Sucking (NNS) on Balance and Gait Measured in 12-42 Month-Old Healthy Children Over 36 Months

NNSbenefits
Start date: November 10, 2019
Phase: N/A
Study type: Interventional

No one disputes that fetal sucking in the womb is a natural human right. Available information on whether, how and when to stop children's sucking habits comes from popular cultural misunderstandings and lack of sound evidence-based results. Because Western countries regard thumb or pacifier (dummy) sucking after a given age as a shameful habit, parents feel stressed, anxious and even guilty for being unable to induce their children to stop non-nutritive sucking (NNS) habits or drag their unwilling child off the soothing-devices, such as pacifiers. Pacifier sucking substantially decreases the incidence of sudden infant death syndrome, reduces pain and crying, and prolongs sleeping time. Of major interest is the hypothesis that NNS improves proprioceptive and exteroceptive development including gait in big mammals (rhesus monkeys). Despite these benefits, available information claims the possible risks induced by prolonging NNS, including psychological shortfall, delayed language skills or dental problems. Despite these claims, authoritative clinical organizations worldwide reach no consensus on the appropriate age at which NNS habits should be stopped. Prompted by conflicting information from primary studies and reviews designed to balance the benefits and risks of NNS habits, our aim in this pilot open randomized controlled trial (RCT) is to test the efficacy of NNS in improving balance and gait in children enrolled at 12-42 months and followed for three years.

NCT ID: NCT03060707 Recruiting - Anesthesia Clinical Trials

Continuous Infusion Versus Intermittent Bolus Injection of Rocuronium

RCVB
Start date: March 23, 2017
Phase: Phase 4
Study type: Interventional

The research is to find out whether continuous infusion of rocuronium requires more or less amount of rocuronium, per kilogram and per hour, than bolus administered rocuronium during noncardiac surgery.

NCT ID: NCT01389791 Recruiting - Muscle Relaxation Clinical Trials

MgSO4 Combined With Rocuronium Priming

Start date: May 2011
Phase: N/A
Study type: Interventional

Priming with either rocuronium or MgSO4 is known to accelerate the effect of rocuronium on muscle relaxation. The purpose of this study is to define the effect of MgSO4 on the rocuronium-priming.