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Muscle Cramp clinical trials

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NCT ID: NCT06432452 Not yet recruiting - Coronary Spasm Clinical Trials

Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm

EDIT-CAS
Start date: August 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this randomized clinical trial is to assess if adjunctive bosentan therapy, in comparison to placebo, can reduce the rate of epicardial vasospasm at follow-up spasm provocation CFT (fuCFT) in patients with previously proven epicardial vasospasm on acetylcholine reactivity testing (at index CFT) and ongoing angina(-like) complaints. Participants will - Use either endothelin receptor antagonist or placebo for 10 weeks - Undergo follow-up acetylcholine spasm provocation test after 10 weeks - Answer online questionnaires on angina and quality of life

NCT ID: NCT06315829 Not yet recruiting - Infantile Spasms Clinical Trials

Artificial Intelligence-based Video Analysis to Detect Infantile Spasms

Start date: August 2024
Phase:
Study type: Observational

Infantile spasms are a type of seizure linked to developmental issues. Unfortunately, they are often misdiagnosed, causing delays in treatment. The purpose of this study is to develop a computer program that can reliably differentiate infantile spasms from similar, yet benign movements in videos. This computer program will learn from videos taken by parents of study participants. Quickly recognizing and treating infantile spasms is crucial for ensuring the best developmental outcomes.

NCT ID: NCT06227676 Completed - Clinical trials for Polycystic Ovary Syndrome

Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25

NUTRITION; GYN
Start date: July 21, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative supplements to dysmenorrhea. The purpose of this clinical trial is to examine the effect of 'Cramp Bites'--classified by a mixture of natural ingredients researched to help with period pain--on women suffering from primary dysmenorrhea: this will be done through providing participants with the snack and surveying them on how it changes their period symptoms.

NCT ID: NCT05980637 Not yet recruiting - Clinical trials for Sleep-related Leg Cramps

Effectiveness and Safety of Shaoyao Gancao Decoction With Addition on the Sleep-related Leg Cramps

Start date: September 1, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

A randomized, double-blinded, placebo-controlled clinical trial using a Chinese Medicine formula in treating Sleep-related Leg Cramps. Subjects will be randomized into a treatment group or placebo group for 4 weeks, and then post-treatment visit at week 6 and week 8.

NCT ID: NCT05861765 Recruiting - Radial Artery Spasm Clinical Trials

The Efficacy of Papaverine to Prevent Radial Artery Spasm During Transradial Cerebral Angiography

PASS
Start date: May 24, 2023
Phase: Phase 2
Study type: Interventional

Rationale:Papaverine is effective on radial artery spasm during transradial cerebral angiography. Purpose: This multicenter, randomized, placebo-controlled, double blind, phase 2b trial aims to investigate the effect and safety of papaverine in treating radial artery spasm during transradial cerebral angiography.

NCT ID: NCT05724485 Completed - Quality of Life Clinical Trials

Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis

Start date: April 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of this randomized controlled trial is to compare the efficacy and safety of branched-chain amino acids (BCAA) versus placebo for treating muscle cramps in cirrhotic patients. The main questions it aims to answer are: - Compared the effect of BCAA versus placebo on muscle cramp frequency in cirrhotic patients - Compared the effect of BCAA versus placebo on muscle cramp duration and severity in cirrhotic patients - Compared the effect of BCAA versus placebo on quality of life in cirrhotic patients with muscle cramps Participants with cirrhosis who have experienced muscle cramps at least once per week will be randomized to receive either a placebo or 12.45 grams of BCAA orally per day for 12 weeks.

NCT ID: NCT05557188 Recruiting - Pregnancy Related Clinical Trials

The Effect of Grounding During Pregnancy

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The study was planned as a randomized controlled trial. The research data included a pregnant informed form, leg cramps evaluation form, Pittsburgh Sleep Quality Index, Visual Analog Scale for fatigue, Pregnancy-Related Anxiety Scale, Short Form-12 Quality of Life Scale, food consumption record form, and pregnancy follow-up form will be used. Questionnaires will be evaluated every two weeks, and the intervention will continue for four weeks in total for each pregnant woman.

NCT ID: NCT05547750 Enrolling by invitation - Clinical trials for Nocturnal Leg Cramps

Effect of Vitamin K2 in the Treatment of Nocturnal Leg Cramps in Older Population

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Nocturnal leg cramps (NLCs) are sudden contractions of the leg muscles, usually in the posterior calf muscles at night, affecting sleep quality. Because the precise pathophysiology of NCLs is unclear, different interventions have been proposed. There is conflicting evidence regarding the efficacy of conventional interventions in preventing cramps. Thus, the present study aims to investigate the effects of vitamin K2 for NLCs in a prospective randomized, double-blind, controlled trial.

NCT ID: NCT05475392 Completed - Neck Pain Clinical Trials

Effects of Post Isometric Relaxation With and Without Stretching Exercises on Neck Pain and Muscle Spasm

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Neck pain is common in the adult general population, disabling and costly Lifetime, which constituted a great problem facing the mother during breast feeding period. The studies showed that poor knowledge and wrong position for breastfeeding influence their own health as well as baby's health. Stretching exercises are one of the manual physical therapy methods that can be used in the treatment of mechanical neck pain) Muscle energy techniques (MET) were originally developed to treat soft tissue, mobilize joints, stretch tight muscles and fascia, reduce pain and to improve circulation and lymphatic drainage. This study aims at applying stretching along with MET technique (post isometric relaxation) to see the combined effect of these two techniques and comparing that group with another one that is only applied stretching and baseline treatment. A randomized clinical trial will be undertaken. Non probability convenient sampling will be used. Forty-six patients with neck pain and muscular spasm will be randomly allocated. Twenty-three participants will be allocated with lottery method in each group. The former group will receive Stretching with MET (post isometric relaxation), and the latter group will receive static stretching only. Both groups will also receive baseline therapy. Treatment will be given once a day daily for 14 days. A visual analogue scale (VAS) will be used to measure the intensity of pain and MMJ questionnaire for muscular spasm. Data will be collected before and at the end of treatment at the 14th day. To analyze data SPSS version 29 will be used.

NCT ID: NCT05457322 Completed - Muscle Cramp Clinical Trials

The RELAX Trial: Nonpharmaceutical Intervention for Nocturnal Muscle Cramps

RELAX
Start date: August 30, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to learn about reducing the symptoms and severity of nighttime lower body muscle cramps in patients with and without cirrhosis. Eligible participants will have an initial 7-day practice phase, followed by 28 days of one of two behavioral interventions.