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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05206253
Other study ID # Bio 2962
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date May 30, 2022
Est. completion date August 31, 2023

Study information

Verified date June 2023
Source University of Saskatchewan
Contact Philip Chilibeck, Ph.D.
Phone 306-966-1072
Email phil.chilibeck@usask.ca
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.


Description:

Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.


Recruitment information / eligibility

Status Recruiting
Enrollment 120
Est. completion date August 31, 2023
Est. primary completion date August 31, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 35 Years
Eligibility Inclusion Criteria: - Resistance training experience for at least one year Exclusion Criteria: - Having taken any nutritional supplements the past 30 days - Currently using anabolic steroids - Currently taking corticosteroids - Allergies to dairy or egg products - Identifying any medical conditions as determined by the "Get Active Questionnaire"

Study Design


Related Conditions & MeSH terms


Intervention

Dietary Supplement:
Whole egg powder
Nutritional supplementation during a 12 week resistance training program
Whey protein powder
Nutritional supplementation during a 12 week resistance training program
Maltodextrin placebo
Nutritional supplementation during a 12 week resistance training program

Locations

Country Name City State
Canada University of Regina Regina Saskatchewan
Canada University of Saskatchewan Saskatoon Saskatchewan

Sponsors (2)

Lead Sponsor Collaborator
University of Saskatchewan Egg Farmers of Canada

Country where clinical trial is conducted

Canada, 

Outcome

Type Measure Description Time frame Safety issue
Primary Change in lean tissue mass Lean tissue mass measured by DXA 12 weeks
Secondary Change in fat mass Fat mass measured by DXA 12 weeks
Secondary Change in biceps muscle thickness biceps muscle thickness measured by ultrasound 12 weeks
Secondary Change in triceps muscle thickness triceps muscle thickness measured by ultrasound 12 weeks
Secondary Change in quadriceps muscle thickness quadriceps muscle thickness measured by ultrasound 12 weeks
Secondary Change in hamstrings muscle thickness hamstrings muscle thickness measured by ultrasound 12 weeks
Secondary Change in bench press strength Bench press strength (kg) 12 weeks
Secondary Change in leg squat strength Leg squat strength (kg) 12 weeks
Secondary Change in knee extension strength Isokinetic knee extension torque 12 weeks
Secondary Change in fasting glucose Fasting glucose 12 weeks
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