Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Muscle Atrophy Clinical Trial

Official title:

Egg Versus Whey Protein as the Optimal Supplement for Fitness-conscious People

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05206253
• Other study ID #: Bio 2962
• Status: Completed
• Phase: N/A
• Start date: May 30, 2022
• Est. completion date: August 31, 2023

Study information

• Verified date: May 2024
• Source: University of Saskatchewan
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Description:

Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 115
• Est. completion date: August 31, 2023
• Est. primary completion date: August 31, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Resistance training experience for at least one year

Exclusion Criteria:

• Having taken any nutritional supplements the past 30 days

• Currently using anabolic steroids

• Currently taking corticosteroids

• Allergies to dairy or egg products

• Identifying any medical conditions as determined by the "Get Active Questionnaire"

Related Conditions & MeSH terms

• Muscle Atrophy
• Muscular Atrophy

Intervention

Dietary Supplement:
• Whole egg powder
Nutritional supplementation during a 12 week resistance training program
• Whey protein powder
Nutritional supplementation during a 12 week resistance training program
• Maltodextrin placebo
Nutritional supplementation during a 12 week resistance training program

Locations

Country	Name	City	State
Canada	University of Regina	Regina	Saskatchewan
Canada	University of Saskatchewan	Saskatoon	Saskatchewan

Sponsors (2)

Lead Sponsor	Collaborator
University of Saskatchewan	Egg Farmers of Canada

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in lean tissue mass	Lean tissue mass measured by DXA	12 weeks
Secondary	Change in fat mass	Fat mass measured by DXA	12 weeks
Secondary	Change in biceps muscle thickness	biceps muscle thickness measured by ultrasound	12 weeks
Secondary	Change in triceps muscle thickness	triceps muscle thickness measured by ultrasound	12 weeks
Secondary	Change in quadriceps muscle thickness	quadriceps muscle thickness measured by ultrasound	12 weeks
Secondary	Change in hamstrings muscle thickness	hamstrings muscle thickness measured by ultrasound	12 weeks
Secondary	Change in bench press strength	Bench press strength (kg)	12 weeks
Secondary	Change in leg squat strength	Leg squat strength (kg)	12 weeks
Secondary	Change in knee extension strength	Isokinetic knee extension torque	12 weeks
Secondary	Change in fasting glucose	Fasting glucose	12 weeks