Serum Neurofilament Light in Multiple Sclerosis

Status Not yet recruiting

Clinical Trial Summary

This prospective cohort study is designed to characterize the utility of sNfL as a biomarker in clinical practice. This study also aims to understand how access to sNfL measures affects patient and clinician knowledge of their disease status and capture how this may have the potential to influence clinical decision-making. Level of disability, cognitive changes, fatigue, depression, and quality of life to detect clinical and subclinical worsening will be measured. While there is strong evidence in support of sNfL as a potential biomarker, literature regarding the application of sNfL in a real-world clinical practice setting is lacking. Understanding the utility of this test to clinicians and patients as a biomarker of MS disease activity is essential. Additionally, the optimum sampling frequency in clinical practice should be investigated to further elucidate its practicality. Given recent advances in the treatment of MS, there is increasing need for convenient and accessible measures of treatment efficacy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
Relapsing Remitting Multiple Sclerosis
Sclerosis

Clinical Trial Details

NCT number	NCT06282081
Study type	Observational
Source	Dent Neuroscience Research Center
Contact
Status	Not yet recruiting
Phase
Start date	March 1, 2024
Completion date	March 1, 2027

View Details

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