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BrainAgeMS - a Comparative Study of Brain Aging in Healthy and Patients With Multiple Sclerosis — BrainAgeMS  

Multiple Sclerosis Clinical Trial

Official title:
Brain Aging - a Comparative Study in Healthy and Patients With Multiple Sclerosis as Model of a Chronic Neuroinflammatory Disorder (BrainAgeMS)

Clinical Trial Summary

The purpose of this study is to investigate new quantitative MRI-sequences for assessment of age-specific data for the prediction of brain aging.

Clinical Trial Description

After being informed about the study, healthy controls and patients with multiple sclerosis giving written informed consent will undergo blood examination (for determination of the biological age using the publicly available R-package algorithm BioAge), clinical examination (for motor, cognitive and psychological parameters) as well as an MRI-investigation with chemical exchange saturation transfer (CEST) and T1-relaxometry on a 7 Tesla MRI. Data from the healthy controls will be used to set up a normative brain age data set, that could be used for example to train a model for brain age prediction. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06221631
Study type Observational
Source Insel Gruppe AG, University Hospital Bern
Contact Alejandro X. León Betancourt, Dr.med.
Phone +41316326093
Email alejandro.betancourt@insel.ch
Status Not yet recruiting
Phase
Start date June 2024
Completion date March 2028
View Details
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