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Artificial Intelligence in Predicting Progression in Multiple Sclerosis Study — AI ProMiS  

Multiple Sclerosis Clinical Trial

Official title:
Artificial Intelligence in Predicting Progression in Multiple Sclerosis Study

Clinical Trial Summary

The study proposal focuses on multiple sclerosis (MS), a chronic incurable disease of the central nervous system (CNS). The MS disease is characterised by recurrent transient disability progression, quantified by increase in the extended disability status score (EDSS), and subsequent remission (disappearance of symptoms and reduced EDSS score) or, alternatively, a gradual EDSS disability progression and exacerbation of associated symptoms. At the same time, the MS is characterised by multifocal inflammatory lesions disseminated throughout the white and grey matter of the CNS, which can be observed and quantified in the magnetic resonance (MR) scans. The proposed study will address the critical unmet need of computer-assisted extraction and assessment of prognostic factors based from an individual patient's brain MR scan, such as lesion count, volume, whole-brain and regional brain atrophy, and atrophied lesion volume, in order to evaluate the capability for personalized future disability progression prediction.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05426980
Study type Observational
Source University of Ljubljana
Contact
Status Completed
Phase
Start date December 13, 2021
Completion date September 30, 2023
View Details
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