Investigation of the Effects of Motor Imagery and Action Observation Training in Individuals With Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:

Investigation of the Effects of Motor Imagery and Action Observation Training on Walking, Fatigue, Trunk Control and Muscle Oxygenation in Individuals With Multiple Sclerosis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05377476
• Other study ID #: 2022-5
• Status: Recruiting
• Phase: N/A
• Start date: June 1, 2022
• Est. completion date: June 1, 2024

Study information

• Verified date: January 2023
• Source: Hacettepe University
• Contact: Melike Sumeyye Ozen, M.Sc.
• Phone: 506 153 06 06
• Email: mcengiz[@]bandirma.edu.tr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

It was planned to examine the effects of motor imagery and action observation training applied in addition to standard rehabilitation in individuals with Multiple Sclerosis on walking, fatigue, trunk control and muscle oxygenation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: June 1, 2024
• Est. primary completion date: May 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Being between the ages of 18-65
• Having a definite diagnosis of MS
• Expanded Disability Status Scale (EDSS) score of 4.0 and below (it is determined routinely by the physician during the examination)
• Not having an attack in the last 3 months

Exclusion Criteria:

• Having another musculoskeletal, cardiovascular, pulmonary, metabolic, or neurological disease severe enough to preclude participation in the study.
• Having severe vision and hearing problems
• Presence of severe cognitive impairment detected by the physician at a level that prevents the tests from being performed.

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

Intervention

Other:
• Motor Imagery training
Individuals included in this group will receive 20 minutes of motor imagery training in addition to 40 minutes of standard rehabilitation.
• Action Observation training
Individuals included in this group will receive 20 minutes of action observation training in addition to 40 minutes of standard rehabilitation.
• standard rehabilitation
40 minutes of standard rehabilitation.

Locations

Country	Name	City	State
Turkey	Hacettepe University	Ankara

Sponsors (2)

Lead Sponsor	Collaborator
Hacettepe University	Bandirma Onyedi Eylül University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	6 Min Walking Test	It will be used to measure walking capacity. Before the test is applied, necessary information will be given to the individuals and they will be asked to walk as fast as possible for 6 minutes on the 30-meter track.	6 week
Primary	Timed Up and Go Test	It will be used to assess the functional mobility of individuals. Individuals will be asked to stand up without support from the chair they are sitting in, and to return from the designated area after walking a distance of 3 meters and sit back on the chair without support.	6 week
Primary	Dynamic Gait Index	It is a scale that evaluates gait balance in MS patients. It examines the balance in completely different walking situations, including daily life activities such as turning the head while walking, taking a step over an obstacle, climbing and descending stairs.	6 week
Primary	Multiple Sclerosis Walking Scale-12	It is a scale used to measure walking capacity.	6 week
Primary	RehaGait® (Hasomed, Magdeburg, Germany) Gait Analysis	The device gives about the time-distance characteristics and kinematic data of the gait.	6 week
Primary	Fatigue Severity Scale	It is a scale that evaluates the extent to which fatigue affects the daily functions of MS patients.	6 week
Primary	Trunk Impairment Scale	It is used to evaluate trunk control.	6 week
Primary	Assessment of the Endurance of Core Muscles	The McGill protocol will be applied to assess the endurance of the core muscles. This protocol consists of a combination of 4 tests; modified Biering-Sorenson test, trunk flexor endurance test, right and left lateral bridge (lateral plank) tests.	6 week
Primary	Assessment of the Strength of Core Muscles	It will be evaluated with "Sit-ups" and Modified "Push-ups" tests.	6 week
Secondary	Kinesthetic and Visual Imagery Questionnaire	It is a tool used to assess individuals' imagery levels.	6 week
Secondary	Movement Imagery Questionnaire-3	It is a tool used to assess individuals' imagery levels.	6 week
Secondary	Mental Stopwatch	Mental stopwatch is a method that enables the objective measurement of motor imagery by examining the time difference between the physical execution of the movement (Movement Execution Time, MET) and the mental visualization of the same movement (Movement Imagery Time, MIT).	6 week
Secondary	Measurement of Muscle Oxygenation	It will be measured over the Quadriceps muscle with the MOXY Monitor Device (saturation, Hb values). The Moxy muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21 mm) device that measures regional blood flow and oxygenation by placing it on the skin non-invasively with near infrared spectroscopy (NIRS).	6 week