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Clinical Trial Summary

Spasticity is a frequent and debilitating symptom in patients with multiple sclerosis (MS). Sustained contractile activity, such as that observed in spastic muscles, could reduce the capillary density and induce important changes in the muscular microcirculation, leading to oxidative changes within the muscular tissue. Such changes reflect altered aerobic metabolism and impaired mitochondrial function. The available therapeutic strategies for treating spasticity and related symptoms are usually faced with limited efficacy and numerous side effects. For these reasons, non-invasive stimulation techniques, namely transcutaneous stimulation by means of Exopulse Mollii suit, might be of help in this context.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05362006
Study type Interventional
Source Institut De La Colonne Vertebrale Et Des Neurosciences
Contact
Status Completed
Phase N/A
Start date March 1, 2022
Completion date May 30, 2023

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