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Cognitive-motor Telerehabilitation in MS — CoMoTeMS  

Multiple Sclerosis Clinical Trial

Official title:
Cognitive-motor Telerehabilitation in Multiple Sclerosis

Clinical Trial Summary

The primary goal of this project is providing evidence that a home-based combined cognitive-motor training program improves cognition in persons with multiple sclerosis (MS), compared to single cognitive and motor rehabilitation. Secondary goals are to assess the effects on walking performance and to identify the mechanisms of improvement and predictors of treatment response. The main backbone of this project will be a randomized controlled two-centre clinical trial, in which an at-home computerised cognitive-motor rehabilitation program using telemedicine aimed at improving working memory in persons with MS will be evaluated. Based on the information gathered during this trial, possible mechanisms of improvement will be identified by analysing anatomical and neurophysiological changes on structural MRI and resting-state and task-related EEG before and after rehabilitation. Furthermore, factors that can predict treatment response to the rehabilitation program will be identified.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05355389
Study type Interventional
Source Universitair Ziekenhuis Brussel
Contact Delphine Van Laethem
Phone +32 2 629 10 45
Email Delphine.Van.Laethem@vub.be
Status Recruiting
Phase N/A
Start date September 1, 2022
Completion date May 2025
View Details
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