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NCT04772495 Clinical Trial

miRNA Biomarkers in Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:
The Potential Candidate miRNA Biomarkers in Multiple Sclerosis

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04772495
Other study ID # 2015/7
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 2015
Est. completion date July 2017

Study information
Verified date February 2021
Source University of Gaziantep
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Multiple Sclerosis (MS) characterized by demyelination and axonal degeneration is a chronic inflammatory disease of the central nervous system (CNS). Recent studies have shown that dysregulated miRNAs alter immune responses, so they may have roles basis on various genetic diseases such as MS and may be potential targets for biomarkers and new therapeutic approaches. In this study, we evaluated the dysregulation of miRNA expression levels at MS and MS stages. We also discussed the potential of these miRNAs to be biomarkers and/or therapeutic targets in MS.

Recruitment information / eligibility
Status Completed
Enrollment 69
Est. completion date July 2017
Est. primary completion date May 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 25 Years and older
Eligibility Inclusion Criteria: - The age of 25 years and above - at least one Central Nervous System (CNS) demyelination event Exclusion Criteria: - with genetic diseases, hypertension, head trauma, neuropsychiatric disease, diabetes mellitus, hypertension, cardiac failure, hepatic failure, renal failure, Thalassemia, Sickle cell disease, iron deficiency, and B12 deficiency

Study Design

Related Conditions & MeSH terms

Intervention

Genetic:
• miRNA
miRNA effect on Multiple sclerosis pathology

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University of Gaziantep

Outcome
Type Measure Description Time frame Safety issue
Primary miRNA expression peripheral blood miRNA expressions intraoperative
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