The Minnesota Manual Dexterity Test As A Measure Of Hand Function in Multiple Sclerosis

Multiple Sclerosis Clinical Trial

Official title:

Upper Limb Assessment in Multiple Sclerosis: The Minnesota Manual Dexterity Test As A Measure Of Hand Function

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04721340
• Other study ID #: 2020/03
• Status: Completed
• Start date: February 2, 2021
• Est. completion date: May 16, 2021

Study information

• Verified date: June 2021
• Source: Istanbul Aydin University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of the study is to report the results of manual dexterity using the Minnesota Manual Dexterity Test in people with Multiple Sclerosis.

Description:

Upper limb can be affected even in early stage in people with Multiple Sclerosis (pwMS). Manual dexterity is important to maintain upper limb function and 9-Hole Peg Test (9HPT) is used as gold standard to assess dexterity in pwMS. There are no studies evaluating manual dexterity with the Minnesota Manual Dexterity Test (MMDT) in pwMS. This study aims to:

1. reporting the results of manual dexterity using the Minnesota Manual Dexterity Test and comparing the test results with healthy volunteers,

2. examining the relationship between MMDT and 9HPT, ABILHAND, grip strength, pinch strength, fatigue.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: May 16, 2021
• Est. primary completion date: May 2, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• (1) age 18-65;

• (2) definitive diagnosis of MS according to McDonald criteria;

• (3) ability to read and write in Turkish.

Exclusion Criteria:

• (1) acute attacks of MS (within 3 months);

• (2) cognitive impairment (Mini Mental test result 24 points and below);

• (3) having spasticity (3 and above according to Modified Ashworth Scale)

• (4) any chronic disease other than MS;

• (5) being addicted to alcohol or drugs,

Related Conditions & MeSH terms

• Multiple Sclerosis
• Sclerosis

Intervention

Other:
• Test Group
Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.
• Control Grup
Individuals who meet the inclusion criteria will be evaluated for manual dexterity, performance, muscle strength and fatigue, respectively, on a predetermined day.

Locations

Country	Name	City	State
Turkey	Istanbul Aydin University	Istanbul	Küçükçekmece

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Aydin University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Minnesota Manual Dexterity Test	to assess manual dexterity, higher scores mean a worse outcome.	baseline (on the predetermined assessment day)
Secondary	9-Hole Peg Test	to assess manual dexterity. higher scores mean a worse outcome.	baseline (on the predetermined assessment day)
Secondary	ABILHAND	to assess for performance of activity. score range 0-46 point, higher scores mean a better outcome.	baseline (on the predetermined assessment day)
Secondary	grip strength	using hand dynamometer. higher scores mean a better outcome.	baseline (on the predetermined assessment day)
Secondary	pinch strength	using pinchmeter. higher scores mean a better outcome.	baseline (on the predetermined assessment day)
Secondary	Fatigue Severity Scale	to assess fatigue. score range 0-7 point, higher scores mean a worse outcome.	baseline (on the predetermined assessment day)