Multiple Sclerosis Clinical Trial
Official title:
Preventing Job Loss Using Acceptance and Commitment Therapy in Vocational Rehabilitation
About 60-70% of people with multiple sclerosis (PwMS) lose employment within 10 years of the
diagnosis. This can be due to complex personal and work-based factors including psychological
factors. MS-PROACTIVE aims to test an online self-help therapy to support PwMS to stay in
work called 'READY for MS'. This is a type of Acceptance and Commitment therapy. It is a way
to provide treatment in a flexible way without people having to go to see a psychologist.
The aim of the treatment is to improve self-efficacy which has been shown to be a significant
factor for helping PwMS who want to work to stay in work.
The research team will initially develop an online version of READY for MS. We will ask 4
PwMS to test the online'READY for MS' and provide feedback and advice on any necessary
changes. We will then recruit and randomise 88 PwMS in Leeds and London who are at risk of
job loss. Participants in the active treatment group will use the online treatment in
addition to their usual care; the control group will receive their usual care. The
participants will complete questionnaires at the start of the study, at 8 weeks and 6 months
measuring time off work and work instability (to measure risk of job loss), self-efficacy,
mood, quality of life, fatigue and the impact of MS. The questionnaire data will be analysed
to test the effectiveness of the treatment. The research team will also interview 4 PwMS at
each site at the start of the study, at 8 weeks and 6 months to find out about their
experience of using READY for MS in more detail. This will help to inform the use of READY
for MS in a larger trial in the future.
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